Essential oils-containing mouthwashes for gingivitis and plaque: Meta-analyses and meta-regression

Haas, Alex Nogueira; Wagner, Tassiane Panta; Muniz, Francisco Wilker Mustafa Gomes; Fiorini, Tiago; Cavagni, Juliano; Celeste, Roger Keller

doi:10.1016/j.jdent.2016.09.001

Cited by 42 publications

(26 citation statements)

References 22 publications

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“…These findings add to the body of data supporting the effectiveness of chlorhexidine and essential oil mouthrinses [18][19][20]. While the two mouthrinses had comparable antigingivitis effectiveness, the chlorhexidine mouthrinse was statistically significantly more effective than the essential oil mouthrinse in reducing supragingival plaque.…”

Section: Discussionmentioning

confidence: 52%

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Comparative Evaluation of Clinical Efficacy of Chlorhexidine, Phenolic and Chitosan Mouthrinses on Plaque and Gingivitis: Single-Centre, Double Blind, Randomized Controlled Clinical Study

HP¹

2017

Austin J Dent

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The present study was conducted to determine the effect of different mouthwash preparations used as supplement to regular oral hygiene measures on plaque and gingivitis.A total of 40 patients with chronic gingivitis demonstrating good oral hygiene were recruited for the study and divided into 4 groups. The subjects were briefed about the nature of the study and informed consents were taken. 4 different mouthwash preparations were given among the 4 groups. They are chlorhexidine digluconate, phenolic (Essential oil), chitosan anti-adhesive mouthwash and placebo (distilled water) for the control group. Clinical parameters including gingival index (Loe-Silness, 1963), plaque index (Turesky modification of Quigley-Hein, 1970) and stain index (Lobene, 1968) were recorded at baseline, 3 weeks and 6 weeks for all 4 groups.Results showed that there is highly statistically significant decrease in plaque and gingival index in chlorhexidine and Essential oil group, statistically significant decrease in chitosan and placebo group. Findings from this study indicate chlorhexidine to be the most effective anti-plaque and anti-gingivitis agent, followed by Essential oil mouthwash with the benefit of reduced staining, thus can be used on long term basis, and whereas chitosan is not significantly effective compared to placebo group.

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Section: Discussionmentioning

confidence: 52%

“…Phenolic mouthrinses similarly have established role on plaque and gingival inflammation [19]. Recent clinical trials [20] conducted have shown effectiveness of EO mouthrinses as had been reported consistently in scientific reports.…”

Section: Results and Statistical Analysismentioning

confidence: 89%

Comparative Evaluation of Clinical Efficacy of Chlorhexidine, Phenolic and Chitosan Mouthrinses on Plaque and Gingivitis: Single-Centre, Double Blind, Randomized Controlled Clinical Study

HP¹

2017

Austin J Dent

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“…Essential oils have been used in the oral cavity for decades, with excellent results as agents that aid mechanical control (Haas et al, 2016). Most are used in mouthwash solutions (Kulkarni, Singh, Jalaluddin, & Mandal, 2017;Thomas, Thakur, & Mhambrey, 2015).…”

Section: ? (To All Analyses)mentioning

confidence: 99%

Antimicrobial activity of copaiba oil (Copaifera ssp.) on oral pathogens: Systematic review

Diefenbach

Muniz

Oballe

et al. 2017

Phytotherapy Research

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Copaifera ssp. produces an oil-resin that presents antiinflammatory, antitumor, antiseptic, germicidal, antifungal, and antibacterial activity. This systematic review aimed to analyze the antimicrobial action of Copaiba oil against oral pathogens, when compared to that of control substances. A search on Medline/PubMed, LILACS, SciELO, EMBASE, and SCOPUS databases were performed up to March 2017. To be included, the studies needed to perform any antimicrobial activity essay, using copaiba oil and a control substance. The antimicrobial effect of each substance, in each study, was extracted. Eleven studies were included, and several copaiba species were used. All studies showed that copaiba oil, regardless of its species, presented a bactericidal and/or bacteriostatic effect in in vitro analyzes. Only one study showed that the antimicrobial effect of the Copaifera officinalis was similar to the one found in chlorhexidine. A higher risk of bias was detected in most of the included studies. The studies demonstrated that the antimicrobial activity of copaiba oil, in most cases, is lower than chlorhexidine, which is considered the gold standard. However, there is great potential against oral bacteria. Further high quality studies are warranted in order to assess the efficacy of copaiba oil on oral pathogens.

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“…The mechanical control of biofilm might be impaired in many instances, especially in patients with motor disabilities or those lacking motivation. As an alternative, antimicrobial substances can be used as adjuncts . Several studies have demonstrated the superiority of chlorhexidine on plaque and gingival inflammation control when compared to a placebo/control treatment .…”

Section: Introductionmentioning

confidence: 99%

Efficacy of an unwaxed dental floss impregnated with 2% chlorhexidine on control of supragingival biofilm: A randomized, clinical trial

Muniz

Lima

Rösing

et al. 2017

J of Invest & Clin Dent

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Aim: In the present study, we evaluated the antiplaque and antigingivitis efficacy of a dental floss impregnated with 2% chlorhexidine digluconate.Methods: Thirty dental students were randomly divided into three groups (n=10): (a) negative control (NC) group, in which no interproximal cleaning was performed; (b) the positive control (PC) group, which used a standard unwaxed dental floss twice daily; and (c) and the test group, which used a unwaxed dental floss impregnated with 2% chlorhexidine twice daily. Six surfaces per tooth were evaluated by the Quigley-Hein plaque index (Turesky modification) at the last appointment (day 15), and testing for the presence of marginal bleeding was performed using the marginal bleeding index (MBI) at both the baseline and last appointments.

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Essential oils-containing mouthwashes for gingivitis and plaque: Meta-analyses and meta-regression

Cited by 42 publications

References 22 publications

Comparative Evaluation of Clinical Efficacy of Chlorhexidine, Phenolic and Chitosan Mouthrinses on Plaque and Gingivitis: Single-Centre, Double Blind, Randomized Controlled Clinical Study

Comparative Evaluation of Clinical Efficacy of Chlorhexidine, Phenolic and Chitosan Mouthrinses on Plaque and Gingivitis: Single-Centre, Double Blind, Randomized Controlled Clinical Study

Antimicrobial activity of copaiba oil (Copaifera ssp.) on oral pathogens: Systematic review

Efficacy of an unwaxed dental floss impregnated with 2% chlorhexidine on control of supragingival biofilm: A randomized, clinical trial

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