Essential Oils and Chemical Diversity of Southeast European Populations of Salvia officinalis L.

Abstract

The essential oils of 25 populations of Dalmatian sage (Salvia officinalis L.) from nine Balkan countries, including 17 indigenous populations (representing almost the entire native distribution area) and eight non-indigenous (cultivated or naturalized) populations were analyzed. Their essential-oil yield ranged from 0.25 to 3.48%. Within the total of 80 detected compounds, ten (β-pinene, 1,8-cineole, cis-thujone, trans-thujone, camphor, borneol, trans-caryophyllene, α-humulene, viridiflorol, and manool) represented 42.60 to 85.70% of the components in the analyzed essential oils. Strong positive correlations were observed between the contents of trans-caryophyllene and α-humulene, α-humulene and viridiflorol, and viridiflorol and manool. Principal component analysis (PCA) on the basis of the contents of the ten main compounds showed that four principal components had an eigenvalue greater than 1 and explained 79.87% of the total variation. Performing cluster analysis (CA), the sage populations could be grouped into four distinct chemotypes (A-D). The essential oils of 14 out of the 25 populations of Dalmatian sage belonged to Chemotype A and were rich in cis-thujone and camphor, with low contents of trans-thujone. The correlation between the essential-oil composition and geographic variables of the indigenous populations was not significant; hence, the similarities in the essential-oil profile among populations could not be explained by the physical proximity of the populations. Additionally, the southeastern populations tended to have higher EO yields than the northwestern ones.

Salvia officinalis L. Essential Oils from Spain: Determination of Composition, Antioxidant Capacity, Antienzymatic, and Antimicrobial Bioactivities

“…The absence of this compound may be regarded as a positive aspect because it is associated with the off‐flavours produced by contamination with mold. Cvetkovikj et al . found a high degree of variability among SoEOs from south‐eastern Europe, even with regard to the main components.…”

Inoculation with arbuscular mycorrhizal fungi alters content and composition of essential oil of Sage (Salvia officinalis) under different phosphorous levels

“…According to Alonso (1998), the sage's EO content commonly ranges from 0.4 to 1.0%. However, Cvetkovikj et al (2015) found EO content variation of 0.25 to 3.48% among twenty-five samples of sage plants across nine Southeast European countries. Govahi et al (2015) observed an averaged EO content of 1.86% in sage plants cultivated under different doses of fertilizers and subjected to water stress.…”

Actividad antiproliferativa de aceites esenciales de plantas cultivadas en Colombia

“…El 46 % de su contenido está constituido de 1,8-cineol, α-tujona y β-cariofileno. En una muestra extraída de una planta del Valle del Cauca se encontraron β-cariofileno y α-copaeno como los constituyentes mayoritarios (Saldarriaga et al, 2009) y los mismos terpenos se identificaron en AEs de plantas de otros países (Cvetkovikj et al, 2015). La actividad antiproliferativa del AE puede deberse a la presencia de estos terpenos, el 1-8-cineol mostró eficacia para inhibir el desarrollo de cáncer colorectal en ratones (Murata et al, 2013) y de los otros terpenos existe evidencia de la actividad anticancerígena como se mencionó.…”