Essential hypertension and membrane lithium transport in depressed patients

Lithium-7 NMR relaxation study of lithium binding in human erythrocytes

“…0006-2960/93/0432-13490S04.00/0 any significant difference with lithium-free patients (Mallinger et al, 1983;Richelson et al, 1986). In contrast, the rates of Na+-Li+ exchange in RBCs from treated and untreated hypertensive patients are significantly higher than those of normotensive individuals (Canessa et al, 1980;Ramasamy et al, 1990).…”

“…Although some researchers have claimed that the rates of Na+-Li+ exchange in RBC suspensions from bipolar patients receiving lithium carbonate are lower than those of normal individuals (Frazer et al, 1978;Greil et al, 1977;Mota de Freitas et al, 1990b;Ramsey et al, 1979), other investigators failed to find t Financial support from USPHS Grant MH45926 from the National * Author to whom correspondence should be addressed. 0006-2960/93/0432-13490$04.00/0 any significant difference with lithium-free patients (Mallinger et al, 1983;Richelson et al, 1986). In contrast, the rates of Na+-Li+ exchange in RBCs from treated and untreated hypertensive patients are significantly higher than those of normotensive individuals (Canessa et al, 1980;Ramasamy et al, 1990).…”