Essential Hematuria in Children—Prognostic Aspects

Livaditis, Alexander; Ericsson, N. O.

doi:10.1111/j.1651-2227.1962.tb06594.x

Cited by 17 publications

(5 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Clinically the 45 patients in groups 1-3 appear to have the syndrome which in the past has been variously described as "essential" (Wylie, 1955;Livaditis and Ericsson, 1962) (Ayoub and Vernier, 1965). This syndrome was described in young adults by Baehr (1926), who emphasized its harmless nature.…”

Section: Discussionmentioning

confidence: 99%

Symptomless Haematuria in Childhood

Glasgow¹,

Moncrieff²,

White³

1970

BMJ

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Symptomless Haematuria in Childhood

Glasgow¹,

Moncrieff²,

White³

1970

BMJ

View full text Add to dashboard Cite

“…Focal lesions were demonstrated on renal biopsy, and at this time 5 years later, 50% of these children have no evidence of renal disease. The experience of Livaditis and Ericsson (1962), who dealt with similar cases clinically but made no tissue evaluation, leads one to believe that the eventual prognosis is good: 36 of 50 children whom they observed for periods ranging from 4 months to 9 years were well and had no haematuria. After 5 years, 50% of the children evaluated by us have persistent disease.…”

Section: Discussionmentioning

confidence: 99%

Recurrent haematuria in childhood. A five-year follow-up.

Johnston¹,

Shuler²

1969

Archives of Disease in Childhood

View full text Add to dashboard Cite

“…Often, such examinations fail to reveal any cause for the haematuria. Many investigators (Baehr, 1926;Livaditis and Ericsson, 1962;Travis et al, 1962;Arneil et al, 1969;Johnston and Shuler, 1969;Glasgow et al, 1970) have concluded that the majority of such patients do not suffer from renal disease and have conferred upon them such diagnoses as 'idiopathic', 'benign', or 'essential' haematuria. In 1965, Ayoub and Vernier first reported a familial incidence of benign haematuria, a finding which has since been substantiated by others (McConville et al, 1966;Marks and Drummond, 1969;Rogers et al, 1973;Cotton et al, 1975).…”

mentioning

confidence: 99%

Benign familial haematuria in children from the Jewish communities of Israel: clinical and genetic studies.

Eisenstein¹,

Stark²,

Goodman³

1979

Journal of Medical Genetics

View full text Add to dashboard Cite

SUMMARY Over 7 years, 130 children were referred for prolonged isolated haematuria of unknown cause. In 34 instances, haematuria was also found in one or more family members. In 23 of these families (18 % of all referrals for isolated haematuria), investigation and follow-up, for periods of 5 to 10 years, of the index cases and of 56 haematuric relatives showed no evidence of renal disease and no other pathological findings. These subjects were diagnosed as having benign familial haematuria.The gene for benign familial haematuria is apparently transmitted as an autosomal dominant with reduced penetrance and variable expressivity. In Israel, the disorder seems to be more frequent among Jews of non-Ashkenazi descent than among those of European ancestry (Ashkenazim).Persistent or recurrent microscopical haematuria in otherwise healthy children represents a rather common clinical problem necessitating diagnostic procedures to identify or rule out renal disease, urinary tract pathology, or a haemorrhagic diathesis. Often, such examinations fail to reveal any cause for the haematuria. Many investigators (Baehr, 1926;Livaditis and Ericsson, 1962;Travis et al., 1962;Arneil et al., 1969;Johnston and Shuler, 1969;Glasgow et al., 1970) have concluded that the majority of such patients do not suffer from renal disease and have conferred upon them such diagnoses as 'idiopathic', 'benign', or 'essential' haematuria. In 1965, Ayoub and Vernier first reported a familial incidence of benign haematuria, a finding which has since been substantiated by others (McConville et al., 1966;Marks and Drummond, 1969;Rogers et al., 1973;Cotton et al., 1975). Since familial aggregation appeared to be a surprisingly common occurrence among children referred to our clinic because of persistent or recurrent haematuria, we decided to investigate all such cases seen over a 7-year period. Of these patients, 23 are believed to have benign familial haematuria (BFH). This paper describes the features on which the diagnosis was based and summarises clinical and genetic findings in this group of subjects.Received for publication 23 December 1978 Subjects and methods During the period 1966 to 1972, 130 children were seen in the Paediatric Nephrology Clinic of the Beilinson Medical Center with isolated, asymptomatic, persistent, or recurrent haematuria for which no cause could be found. This was defined as the finding of more than 10 erythrocytes per highpower field in 80 % or more of repeated urine examinations performed over a period of at least one year, and Addis counts showing more than 1 5 million erythrocytes per 12 h (our findings in healthy children are less than 0 5 million). In such cases urine analyses were performed on members of the immediate family (sibs and parents) and a family history was taken relating to renal disease, urinary findings, hypertension, deafness, and ocular anomalies. In 34 instances, haematuria was discovered in one or more members of the patient's family as a result of this search.The following investigations were ...

show abstract

Essential Hematuria in Children—Prognostic Aspects

Cited by 17 publications

References 7 publications

Symptomless Haematuria in Childhood

Symptomless Haematuria in Childhood

Recurrent haematuria in childhood. A five-year follow-up.

Benign familial haematuria in children from the Jewish communities of Israel: clinical and genetic studies.

Contact Info

Product

Resources

About