ESR/Alanine γ-dosimetry in the 10–30 Gy range

Fainstein, C.; Winkler, E.; Saravi, M.

doi:10.1016/s0969-8043(00)00070-1

Cited by 17 publications

(8 citation statements)

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“…Qualitatively, there are blood irradiation indicators, used routinely, which only state whether or not the blood bag was irradiated. Different quantitative dosimetric tools have been studied for blood dosimetry in recent years: thermoluminescent dosimetry (TLD) [94,112,113], Fricke solution [112], radiochromic film [114], colorimetric dosimetry [115] and solid state dosimetry, including methacrylate polymers (red perspex) [94], alanine [94,[116][117][118], mosfet [41] and diodes [119]. A quantitative method is commercially available for blood irradiators dosimetry (DOSE-MAP TM /Ashland Inc., Covington, Kentucky, USA).…”

Section: Discussionmentioning

confidence: 99%

Correction: Prevention of Transfusion-Associated Graft-versus-Host Disease by Irradiation: Technical Aspect of a New Ferrous Sulphate Dosimetric System

Lama¹,

GÃ3es²,

Petchevist³

et al. 2014

PLoS ONE

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Irradiation of whole blood and blood components before transfusion is currently the only accepted method to prevent Transfusion-Associated Graft-Versus-Host-Disease (TA-GVHD). However, choosing the appropriate technique to determine the dosimetric parameters associated with blood irradiation remains an issue. We propose a dosimetric system based on the standard Fricke Xylenol Gel (FXG) dosimeter and an appropriate phantom. The modified dosimeter was previously calibrated using a 60 Co teletherapy unit and its validation was accomplished with a 137 Cs blood irradiator. An ionization chamber, standard FXG, radiochromic film and thermoluminescent dosimeters (TLDs) were used as reference dosimeters to determine the dose response and dose rate of the 60 Co unit. The dose distributions in a blood irradiator were determined with the modified FXG, the radiochromic film, and measurements by TLD dosimeters. A linear response for absorbed doses up to 54 Gy was obtained with our system. Additionally, the dose rate uncertainties carried out with gel dosimetry were lower than 5% and differences lower than 4% were noted when the absorbed dose responses were compared with ionization chamber, film and TLDs.

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Section: Discussionmentioning

confidence: 99%

Correction: Prevention of Transfusion-Associated Graft-versus-Host Disease by Irradiation: Technical Aspect of a New Ferrous Sulphate Dosimetric System

Lama¹,

GÃ3es²,

Petchevist³

et al. 2014

PLoS ONE

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“…The data points shown in Finally, in Fig. 5 we compare data from both the amino acid L-Alanine (5) and the biogenic mineral from GL, in the blood irradiation range, from 15Gy to 50Gy (6,7). .…”

Section: Epr Of γ-Irradiated Samplesmentioning

confidence: 99%

Glycymeris Longior shells, an alternative gamma radiation reference detector

Fainstein¹

2006

Braz. J. Phys.

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Gamma irradiation of biogenic calcium carbonate, from fossil shells of species Glycymeris Longior, results in the formation of CO 2− centers, as measured by electron paramagnetic resonance spectroscopy. The spectral line intensity increases linearly with increasing dose, without distortion, up to 50Gy. Fitting of the data yields the equation, Dose[Gy]=-0.8(0.6)+0.0258(0.0004)×[dχ"/dH]pp/mg.Over a year control measurements show no significative change in the data.

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“…Ion recombination effects in ionisation chambers generally preclude their use at these high dose rates (Boag 1950 , Boag and Currant 1980 , Gotz et al 2017 ). Hence, offline dosimeters like alanine and film are the preferred dosimeters (Fainstein et al 2000 , Hayes et al 2000 ). To date, most preclinical work has been performed using electron beams generated by linear accelerators (linacs) of energies 4–20 MeV (Schüler et al 2017 , Jaccard et al 2018 , Lempart et al 2019 ).…”

Section: Introductionmentioning

confidence: 99%

Monitoring electron energies during FLASH irradiations

Berne¹,

Petersson²,

Tullis³

et al. 2021

Phys. Med. Biol.

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When relativistic electrons are used to irradiate tissues, such as during FLASH pre-clinical irradiations, the electron beam energy is one of the critical parameters that determine the dose distribution. Moreover, during such irradiations, linear accelerators (linacs) usually operate with significant beam loading, where a small change in the accelerator output current can lead to beam energy reduction. Optimisation of the tuning of the accelerator’s radio frequency system is often required. We describe here a robust, easy-to-use device for non-interceptive monitoring of potential variations in the electron beam energy during every linac macro-pulse of an irradiation run. Our approach monitors the accelerated electron fringe beam using two unbiased aluminium annular charge collection plates, positioned in the beam path and with apertures (5 cm in diameter) for the central beam. These plates are complemented by two thin annular screening plates to eliminate crosstalk and equalise the capacitances of the charge collection plates. The ratio of the charge picked up on the downstream collection plate to the sum of charges picked up on the both plates is sensitive to the beam energy and to changes in the energy spectrum shape. The energy sensitivity range is optimised to the investigated beam by the choice of thickness of the first plate. We present simulation and measurement data using electrons generated by a nominal 6 MeV energy linac as well as information on the design, the practical implementation and the use of this monitor.

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ESR/Alanine γ-dosimetry in the 10–30 Gy range

Cited by 17 publications

References 0 publications

Correction: Prevention of Transfusion-Associated Graft-versus-Host Disease by Irradiation: Technical Aspect of a New Ferrous Sulphate Dosimetric System

Correction: Prevention of Transfusion-Associated Graft-versus-Host Disease by Irradiation: Technical Aspect of a New Ferrous Sulphate Dosimetric System

Glycymeris Longior shells, an alternative gamma radiation reference detector

Monitoring electron energies during FLASH irradiations

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