Espondilodiscitis infecciosas en un área sanitaria gallega, 1983-2003

Rodríguez, Norberto Gómez; Bellas, Yolanda Penelas-Cortés; Ruán, Jesús Ibáñez; Pérez, Marisol González; Lorenzo, Marta

doi:10.4321/s0212-71992004001100003

Cited by 12 publications

(6 citation statements)

References 17 publications

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“…[14] In our study, half of patients (11 of 22) presented with other active focus of extravertebral TB, especially, lung and nodal disesase. This percentage is high in comparison with other studies, [15] but is similar with the description of Gómez Rodriguez et al [16] that included 76 cases of spondilodiscitis with 48% of active extraspinal TB. Weng et al [17] published a 32% of association between spinal and pulmonary TB.…”

Section: Discussionsupporting

confidence: 89%

Spondilodiscitis due to Mycobacterium tuberculosis in HIV and non-HIV-infected patients: Eleven years experience in a referent Hospital of infectious diseases in Argentina

Corti¹,

Villafañe²,

Trione³

et al. 2012

Ann Trop Med Public Health

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Background: Tuberculosis (TB) is an emerging health problem despite the advances in the methods of diagnosis and treatment. The resurgence of tuberculous spondilodiscitis (TBSD) or Pott's disease can be expected to be associated with a concomitant increase in the incidence of extra-pulmonary TB. Aim: To describe the clinical features, imaging findings, and laboratory diagnosis in a group of patients with TBSD. Materials and Methods: From January 1 st 2000 to December 31 st 2010, we retrospectively reviewed 22 cases of spinal TB. Only those with positive culture results and/or characteristic clinical and pathological findings were enrolled. Demographic data, comorbilities, clinical manifestations, time up to the definitive diagnosis, outcome and sequelae were considered. Results: During the study period, 22 patients were diagnosed with TBSD; 14 were men and 8 women with a median of age of 34 years at the time of diagnosis. The median duration of symptoms before the TBSD diagnosis was 120 days (range 30 to 360 days). At the time of diagnosis, fever and back pain were the most common clinical symptoms; 7 patients (32%) had fever and 21 (95%) had spinal pain; eleven patients (50%) had constitutional symptoms; 6 (27%) had respiratory symptoms and 3 (13.6%) had neurological manifestations. Magnetic resonance imaging (MRI) was performed in 9 (40%) cases, computed tomography (CT) in 7 patients (32%), and abdominal ultrasound in 6 cases (27%). The lumbar spine was the most commonly involved site (14 patients, 64%); thoracic spine was involved in 2 patients (9%); dorsolumbar spine was compromised in 4 cases (18%). Cervical spine was only involved in one patient (4.5%) and the last patient (4.5%) presents a global spinal involvement (cervical-thoracic and lumbar spine). Conclusion: Insidious clinical course and ambiguous manifestations of TBSD often delay the accuracy of diagnosis. Spinal TB should be included in the differential diagnosis of patients with prolonged back pain and fever.

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Section: Discussionsupporting

confidence: 89%

Spondilodiscitis due to Mycobacterium tuberculosis in HIV and non-HIV-infected patients: Eleven years experience in a referent Hospital of infectious diseases in Argentina

Corti¹,

Villafañe²,

Trione³

et al. 2012

Ann Trop Med Public Health

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“…111 Of note, all 10 included studies were reflective of HICs. 17,24,62,66,69,75,101,110,157,160,185 This does not imply that the incidence of non-TB spondylodiscitis is zero for all LICs and MICs, but rather that it is simply not known. Note, however, that the high incidence in HICs indicates that vertebral osteomyelitis may be a disease afflicting the developed world.…”

Section: Nontuberculous Osteomyelitismentioning

confidence: 99%

Epidemiology of central nervous system infectious diseases: a meta-analysis and systematic review with implications for neurosurgeons worldwide

Robertson

Lepard

Mekary

et al. 2019

Journal of Neurosurgery

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OBJECTIVE Central nervous system (CNS) infections cause significant morbidity and mortality and often require neurosurgical intervention for proper diagnosis and treatment. However, neither the international burden of CNS infection, nor the current capacity of the neurosurgical workforce to treat these diseases is well characterized. The objective of this study was to elucidate the global incidence of surgically relevant CNS infection, highlighting geographic areas for targeted improvement in neurosurgical capacity. METHODS A systematic literature review and meta-analysis were performed to capture studies published between 1990 and 2016. PubMed, EMBASE, and Cochrane databases were searched using variations of terms relating to CNS infection and epidemiology (incidence, prevalence, burden, case fatality, etc.). To deliver a geographic breakdown of disease, results were pooled using the random-effects model and stratified by WHO region and national income status for the different CNS infection types. RESULTS The search yielded 10,906 studies, 154 of which were used in the final qualitative analysis. A meta-analysis was performed to compute disease incidence by using data extracted from 71 of the 154 studies. The remaining 83 studies were excluded from the quantitative analysis because they did not report incidence. A total of 508,078 cases of CNS infections across all studies were included, with a total sample size of 130,681,681 individuals. Mean patient age was 35.8 years (range: newborn to 95 years), and the male/female ratio was 1:1.74. Among the 71 studies with incidence data, 39 were based in high-income countries, 25 in middle-income countries, and 7 in low-income countries. The pooled incidence of studied CNS infections was consistently highest in low-income countries, followed by middle- and then high-income countries. Regarding WHO regions, Africa had the highest pooled incidence of bacterial meningitis (65 cases/100,000 people), neurocysticercosis (650/100,000), and tuberculous spondylodiscitis (55/100,000), whereas Southeast Asia had the highest pooled incidence of intracranial abscess (49/100,000), and Europe had the highest pooled incidence of nontuberculous vertebral spondylodiscitis (5/100,000). Overall, few articles reported data on deaths associated with infection. The limited case fatality data revealed the highest case fatality for tuberculous meningitis/spondylodiscitis (21.1%) and the lowest for neurocysticercosis (5.5%). In all five disease categories, funnel plots assessing for publication bias were asymmetrical and suggested that the results may underestimate the incidence of disease. CONCLUSIONS This systematic review and meta-analysis approximates the global incidence of neurosurgically relevant infectious diseases. These results underscore the disproportionate burden of CNS infections in the developing world, where there is a tremendous demand to provide training and resources for high-quality neurosurgical care.

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“…Bursitis may develop due to nonspecific or specific infections, arthritis and minor and major trauma [1,[4][5][6][7]. Bursitis is treated conservatively with drainage, compressive bandages, cold pack applications and nonsteroidal anti inflammatory drugs [8] which take 2 to 3 weeks to have an effect.…”

Section: Discussionmentioning

confidence: 99%

Treatment of nonseptic bursitis with endoscopic surgery

et al. 2015

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ÖZETAmaç: Amacımız, nonseptik bursitlerde endoskopik cerrahinin yara problemleri, hareket açıklıkları ve işe erken dönüş açısından çok önemli faydalar sağladığını göste-ren kabul edilebilir bir işlem olduğunu göstermektir. Sonuç: Endoskopik bursektomi kısa ameliyat ve işe dön-me süresi, minimal yara problemleri ve mükemmel sonuç-lar nedeniyle güvenilir ve uygulanabilir bir işlemdir.Anahtar kelimeler: Bursit, endoskopi, tedavi ABSTRACT Objective: The aim of this study was to show that endoscopic surgery is a simple and acceptable method for various problems associated with wounds, range of motion and that such surgery ensures an early return to work after treatment of nonresponding nonseptic bursitis. Methods:Thirty-two patients with nonseptic bursitis caused by repeated minor trauma that did not respond to medical treatment from 2008 to 2012 were included in this study. Radiographic [anteroposterior and lateral], ultrasound, macro and microscopic analyses of drainage liquid and aerobic and anaerobic cultures were obtained from the patients for the diagnosis. Results:The mean age was 40.8 years. Fifteen patients had prepatellar bursitis, 13 had olecranon bursitis and 4 had ankle bursitis. Two patients had a history of falling on their knee. The other patients had a history of repetitive stimulation .The mean follow up period was 2.6 years [range. 2-5 years] and no medical complications occurred after the endoscopic surgery; such as scarring, loss of sensation and infection. One recurrence in response to medical treatment was observed. Conclusion:Endoscopic bursectomy is a short and acceptable procedure with excellent results in terms of returning to work early and minimal wound related problems. J Clin Exp Invest 2015; 6 (3): 220-223

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Espondilodiscitis infecciosas en un área sanitaria gallega, 1983-2003

Cited by 12 publications

References 17 publications

Spondilodiscitis due to Mycobacterium tuberculosis in HIV and non-HIV-infected patients: Eleven years experience in a referent Hospital of infectious diseases in Argentina

Spondilodiscitis due to Mycobacterium tuberculosis in HIV and non-HIV-infected patients: Eleven years experience in a referent Hospital of infectious diseases in Argentina

Epidemiology of central nervous system infectious diseases: a meta-analysis and systematic review with implications for neurosurgeons worldwide

Treatment of nonseptic bursitis with endoscopic surgery

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