Esophageal Squamous Papilloma in a Pediatric Patient With <i>Helicobacter pylori</i> Gastritis

Yang, Qi; Stefanovici, Camelia; Mujawar, Quais; El‐Matary, Wael

doi:10.1177/1093526617701798

Cited by 4 publications

(4 citation statements)

References 1 publication

(1 reference statement)

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“…Some cases of OSP in children have reported the presence of H. pylori in the gastric mucosa 15 and the simultaneous diagnosis of EoE 16 ; similarly, in this case series, we found one patient of each.…”

Section: Discussionsupporting

confidence: 80%

“…14 In our study, we found an increase in the number of cases of OSP, especially in 2022 (figure 1); even though, in the last years, fewer UGEs have been performed in children in Hospital Metropolitano de Quito, probably due to the COVID-19 pandemic. We did not find an association with HPVfigure 1 Some cases of OSP in children have reported the presence of H. pylori in the gastric mucosa 15 and the simultaneous diagnosis of EoE 16 ; similarly, in this case series, we found one patient of each.…”

Section: Discussionsupporting

confidence: 57%

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Oesophageal squamous papilloma in paediatric population: a single-centre case series

Almeida

Vásconez-Muñoz

Vásconez-Montalvo

et al. 2023

bmjpo

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PurposeOesophageal squamous papilloma (OSP) is a rare epithelial lesion with an unclear aetiology, found incidentally in upper gastrointestinal endoscopy (UGE). We evaluate the epidemiology, general features and endoscopic and histological characteristics of OSP in children in a single centre.MethodsWe conducted a retrospective search of 3568 medical records of children under 18 years old who underwent UGE between 2004 and 2022, at Hospital Metropolitano de Quito, Ecuador. We described the general features of 15 patients diagnosed with OSP. Histopathology reports were analysed, including a chromogenic in situ hybridisation (CISH) for human papillomavirus (HPV) 6/11.ResultsOSP was diagnosed in 15 patients between 10 and 16 years of age, with an estimated prevalence of 0.4%. The gender ratio male to female was 1:1.1. Most patients (n=14) underwent UGE due to abdominal pain. Lesions were found predominantly in the upper and lower part of the oesophagus; 12 patients had isolated lesions, and none of the lesions tested positive for HPV on CISH 6/11 analysis. Additionally,Helicobacter pyloriand eosinophilic oesophagitis (EoE) were diagnosed in one patient each.ConclusionOur study describes the clinical features of paediatric OSP in a single centre. The prevalence was similar to that in the adult population but higher than in other paediatric populations, and none of our patients had HPV.

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Section: Discussionsupporting

confidence: 80%

Section: Discussionsupporting

confidence: 57%

Oesophageal squamous papilloma in paediatric population: a single-centre case series

Almeida

Vásconez-Muñoz

Vásconez-Montalvo

et al. 2023

bmjpo

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“…The patient we present here had a single papilloma in the distal esophagus and did not have eosinophilic esophagitis and dermal hypoplasia. H. pylori infection was also suggested as a potential underlying etiology in one study reporting a 10-year-old child with ESCP (11). However, there has been no further evidence indicating an association between H. pylori gastritis and ESCP in the pediatric and adult literature.…”

Section: Discussionmentioning

confidence: 99%

Esophageal squamous cell papilloma in a child with cystic fibrosis: A rare incidental endoscopic finding

Gümüş

Orhan

Saltık-Temizel

2023

Akademik Gastroenteroloji Dergisi

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Esophageal squamous cell papilloma is an uncommon epithelial lesion of the esophagus. Epidemiological data regarding esophageal squamous cell papilloma in children is scarce and consists of few case reports. Although the etiology of esophageal squamous cell papilloma remains unclear, chemical/mechanical irritation induced hyper-regenerative response of esophageal mucosa and human papillomavirus infection have been suggested as most probable causes. A case of a 14-year-old girl with cystic fibrosis and chronic dyspepsia had a 0.5 x 0.5 cm sessile, multilobulated, whitish and verrucous polypoid mass close to the lower esophageal sphincter removed. Histologically, a benign squamous papilloma was confirmed. Her dyspeptic symptoms suggestive for gastroesophageal reflux resolved after papilloma removal and anti-acid treatment. Esophageal squamous cell papilloma is an incidental finding at upper endoscopy. Gastroesophageal reflux disease may be responsible for distally localized papillomas. Due to its rarity in childhood, there are not any well-established management and surveillance guidelines. Esophageal squamous cell papilloma should be removed, when possible, because of the ambiguity about its malignant potential.

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“…Incidentally, 2 of the 4 cases were simultaneously diagnosed with HPV-related ESP and H. pylori gastritis and were treated with antibiotics as well as PPI. There has been 1 additional case report of ESP associated H. pylori gastritis, but the HPV test was negative ( 9 ). The presence of H. pylori in our 2 cases may have been the underlying inflammatory condition and could be considered a risk factor for ESP development.…”

Section: Discussionmentioning

confidence: 99%

Esophageal Squamous Papilloma in the Pediatric Population

et al. 2022

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Esophageal squamous papillomas (ESP) are rare benign tumors of the esophagus, which occur mostly in the adult population. Few cases have been reported in children and due to the low incidence, the pathogenesis of ESP is not entirely understood and the management is not standardized. It is thought that mucosal irritation from underlying inflammation, perhaps from GERD, trauma or human papilloma viruses can play a role in the formation of ESP. This report describes 4 cases of pediatric ESP from a single center and discusses the management of these lesions, including the use of antacids and the human papilloma viruses vaccine as treatment modalities. Given the limited data on ESP in the pediatric population, this report aims to describe the management of this condition in 1 center.

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Esophageal Squamous Papilloma in a Pediatric Patient With Helicobacter pylori Gastritis

Cited by 4 publications

References 1 publication

Oesophageal squamous papilloma in paediatric population: a single-centre case series

Oesophageal squamous papilloma in paediatric population: a single-centre case series

Esophageal squamous cell papilloma in a child with cystic fibrosis: A rare incidental endoscopic finding

Esophageal Squamous Papilloma in the Pediatric Population

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