Esophageal Squamous Cell Papillomatosis Arising in Focal Dermal Hypoplasia in a 3‐Year‐Old Girl

Nasr, Youssef; Salgado, David; Demellawy, Dina El; Boland, Margaret; Nanassy, Joseph de

doi:10.1097/mpg.0000000000001899

Cited by 4 publications

(2 citation statements)

References 11 publications

(16 reference statements)

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“…However, higher prevalence of GERD in cystic fibrosis patients might be related with development of ESCP in this patient population. The distal localization of the lesion, the absence of other significant mechanical/chemical irritants, negative histologic findings for HPV infection, and higher on of squamous papillomas, the esophageal papillomas are hypothesized to be related to the high frequency of severe gastroesophageal reflux starting in infancy (9). A potential association between esophageal papillomas and eosinophilic esophagitis has been recently reported in a pediatric case with focal dermal hypoplasia (10).…”

Section: Discussionmentioning

confidence: 99%

Esophageal squamous cell papilloma in a child with cystic fibrosis: A rare incidental endoscopic finding

Gümüş

Orhan

Saltık-Temizel

2023

Akademik Gastroenteroloji Dergisi

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Esophageal squamous cell papilloma is an uncommon epithelial lesion of the esophagus. Epidemiological data regarding esophageal squamous cell papilloma in children is scarce and consists of few case reports. Although the etiology of esophageal squamous cell papilloma remains unclear, chemical/mechanical irritation induced hyper-regenerative response of esophageal mucosa and human papillomavirus infection have been suggested as most probable causes. A case of a 14-year-old girl with cystic fibrosis and chronic dyspepsia had a 0.5 x 0.5 cm sessile, multilobulated, whitish and verrucous polypoid mass close to the lower esophageal sphincter removed. Histologically, a benign squamous papilloma was confirmed. Her dyspeptic symptoms suggestive for gastroesophageal reflux resolved after papilloma removal and anti-acid treatment. Esophageal squamous cell papilloma is an incidental finding at upper endoscopy. Gastroesophageal reflux disease may be responsible for distally localized papillomas. Due to its rarity in childhood, there are not any well-established management and surveillance guidelines. Esophageal squamous cell papilloma should be removed, when possible, because of the ambiguity about its malignant potential.

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Section: Discussionmentioning

confidence: 99%

Esophageal squamous cell papilloma in a child with cystic fibrosis: A rare incidental endoscopic finding

Gümüş

Orhan

Saltık-Temizel

2023

Akademik Gastroenteroloji Dergisi

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“…Two of them were proved to carry a PORCH gene mutation. Nasr [ 38 ] proposed that EPS could be the gastrointestinal phenotypic manifestation of Goltz syndrome. In a four-generation family with angioma serpiginosum (AS), among the six female patients, two sisters of the third generation had EPS [ 42 ].…”

Section: Etiology Of Epsmentioning

confidence: 99%

Esophageal papillomatosis: an exceedingly rare disease

Yan

et al. 2023

Orphanet J Rare Dis

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If esophageal papilloma (EP) is a rare condition, esophageal papillomatosis (EPS) is a distinct rarity. To date, only 53 well documented cases have been described in English literature. However, the number of reports on EPS significantly increased to over 40 cases during the past 20 years. Perhaps, this is due to the broad use of endoscopy and related research achievements. Most of the cases are individual and it seems that there are no associations between them. And up to now no guidelines can be followed. To further understand this exceedingly rare disease, we had a comprehensive review of the epidemiology, etiology, clinical manifestations, pathogenesis, treatment, and clinical course of EPS.

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Cutaneous Diseases of the Esophagus

Camilleri

2021

The Esophagus

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Esophageal Squamous Cell Papillomatosis Arising in Focal Dermal Hypoplasia in a 3‐Year‐Old Girl

Cited by 4 publications

References 11 publications

Esophageal squamous cell papilloma in a child with cystic fibrosis: A rare incidental endoscopic finding

Esophageal squamous cell papilloma in a child with cystic fibrosis: A rare incidental endoscopic finding

Esophageal papillomatosis: an exceedingly rare disease

Cutaneous Diseases of the Esophagus

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