Esophageal squamous cell carcinoma presenting with systemic arterial embolism

Sentani, Kazuhiro; Nakanishi, Yukihiro; Ojima, Hidenori; Hamaguchi, Tetsuya; Shimoda, Tadakazu

doi:10.1111/j.1440-1827.2006.02067.x

Cited by 4 publications

(2 citation statements)

References 12 publications

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“…But a study presents the case of a patient who was diagnosed with acute arterial occlusion in his left lower limb. Following embolectomy, it was found that the embolus originated in the esophageal squamous carcinoma [86]. Pulmonar y thombembolism is a consequence of deep venous thrombosis, thus, anticoagulant profilactic therapy is very important, knowing the procoagulant neoplastic state [87,88].…”

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confidence: 99%

Differential Diagnosis in Esophageal Cancer. Review on literature

Popa¹,

Badiu²,

Andronache³

et al. 2019

Rev. Chim.

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Esophageal cancer represents a neoplasm that is thought to have both an increased incidence and prevalence in the following years. Although much progress has been made in the detection and the early treatment of esophageal cancer, the prognosis is still limited, and mortality remains very high. The most common histological types of esophageal cancer are squamous cell carcinoma, and, respectively, adenocarcinoma. Lately, there has been an accelerated increase in the incidence of adenocarcinoma, in the context of increased prevalence of gastro-esophageal reflux disease and obesity, but also of the current alimentary diet, especially in developed countries. The esophagus has its anatomical features. Moreover, it is located topographicallyin a complex cervico-thoraco-abdominal area, unique for a viscus. From the clinical point of view, the onset of symptoms of esophageal cancer is insidious. For these reasons, special attention should be pain in the early detection and differentiation of this neoplasm from other pathologies. These pathologies are very varied and may comprise other esophageal diseases, neighborhood pathologies such as cervical, thoracic, abdominal, systemic pathologies (immunologic, infectious) or other pathologies such as the oro-maxillo-facial, oculo-orbital, vascular, muscular, and cutaneous ones. Keywords: esophagus, cancer, differential diagnosis

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mentioning

confidence: 99%

Differential Diagnosis in Esophageal Cancer. Review on literature

Popa¹,

Badiu²,

Andronache³

et al. 2019

Rev. Chim.

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“…Arterial tumor embolism is a rare complication in cancer patients. Fewer than 70 cases have been reported . Most of them are associated with primary or secondary pulmonary malignancies, which occurred during intraoperative and postoperative periods.…”

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confidence: 99%

Massive tumor embolism in the abdominal aorta from pulmonary squamous cell carcinoma: Case report and review of the literature

Ohshima

Tsujii

Sakai

et al. 2017

Pathology International

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Acute arterial tumor embolism is a rare complication in cancer patients. Most of the previously reported cases of arterial tumor embolism have been associated with pulmonary malignancies and occurred during the intraoperative and postoperative periods. Very few cases occurred spontaneously. To our knowledge, there is no previous report of spontaneous and massive tumor embolism occluding the abdominal aorta in patients suffering from primary pulmonary carcinoma. We describe the case of 64-year-old man who presented with left homonymous hemianopsia and backache. Further evaluation revealed a mass in the right lung, severe coagulopathy, and cerebral hemorrhagic infarction in the right occipital lobe. He suddenly developed lower limb ischemia 4 weeks after his first clinical visit, and finally, died of multiple organ failure. Autopsy showed non-keratinizing squamous cell carcinoma in the right lung and massive tumor emboli in the abdominal aorta containing nests of squamous cell carcinoma. Infarct regions were found in the bilateral kidneys, spleen, liver, and brain; fibrin thrombi, but not tumor emboli, were found in these regions. This case suggested that tumor embolism should be considered when patients suffering from primary pulmonary malignancies develop arterial embolism and arterial tumor emboli could be massive enough to occlude the abdominal aorta.

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