Esophageal motor disorders in patients evaluated for dysphagia and/or noncardiac chest pain

Bassotti, Gabrio; Pelli, Maria Antonietta; Morelli, Antonio

doi:10.1007/bf02493414

Cited by 15 publications

(7 citation statements)

References 38 publications

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“…Experimental techniques. Esophageal manometry was carried out in accordance with a previously described technique and equipment (16)(17)(18). Briefly, an 8-lumcn polyvinyl chloride (PVC) manometric catheter was used, with the 4 distal side holcs arranged radially at the same level at 90" and the proximal holes spaced 5 cm apart (type ESM 3R; Arndorfer Medical Specialties, Greendale, WI).…”

Section: Methodsmentioning

confidence: 99%

Esophageal dysfunction in scleroderma. Relationship with disease subsets

Bassotti

Battaglia

Debernardi

et al. 1997

Arthritis & Rheumatism

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Objective. To investigate the relationship between esophageal function and the extent of disease in a nonselected group of scleroderma patients, and to study gastric and small bowel motility in a group of scleroderma patients with more severe clinical manifestations.Methods. Esophageal function in 125 scleroderma patients was investigated by radiologic, endoscopic, manometric, and pH-metric techniques. Ten patients also underwent gastrointestinal (GI) manometric recording, both during fasting and after a standard meal.Results. Radiologic abnormalities of the esophagus were found in 55 of 81 patients (68%) and esophagitis in 45 of 125 (36%). No significant relationship was disclosed between GI symptoms, radiologic abnormalities, esophagitis grade, and the various disease subsets. However, the overall incidence of endoscopic esophagitis (irrespective of the degree) was significantly (P < 0.05) correlated with the patient subgroups, with 100% incidence of esophagitis in those having the more severe cutaneous involvement (type 111). Manometric abnormalities were documented in 80% of patients, and pathologic reflux in 78%. The severity of esophageal abnormalities on manometry significantly correlated with the severity of the disease, whereas no correlations were found with pH-metric data. Ninety percent of the . ~~~~~

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Section: Methodsmentioning

confidence: 99%

Esophageal dysfunction in scleroderma. Relationship with disease subsets

Bassotti

Battaglia

Debernardi

et al. 1997

Arthritis & Rheumatism

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“…As detailed in Table 31.6, summarizing representative studies of at least 30 subjects, manometric abnormalities are prevalent among these groups [128,135,[159][160][161][162][163][164][165][166][167][168]. Thus, the only way to estimate the incidence or prevalence of spastic disorders is to examine the data on populations at risk and reference the observed frequency of spastic disorders to the incidence of achalasia, which, as detailed earlier, is about 1/100 000 population per year.…”

Section: Epidemiologymentioning

confidence: 99%

Motility Disorders of the Esophagus

Kahrilas

Pandolfino

2008

Textbook of Gastroenterology

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“…Manometric tracings were analyzed according to previously published criteria [13], taking into account the following variables: (1) LES presCorrespondence to: Gabrio Bassotti, M.D., Ph.D., Laboratorio di Motilità Intestinale, Clinica di Gastroenterologia ed, Endoscopia Digestiva, Policlinico Monteluce, 06100 Perugia, Italy Dysphagia 13: 28-31 (1998) sure, recorded in mmHg as an average of four individual pressures, was measured at midexpiration, with mean gastric pressure taken as baseline. Average values less than 10 mmHg were regarded as an abnormally low LES pressure.…”

Section: Discussionmentioning

confidence: 99%

Esophageal Manometric Abnormalities in Parkinson's Disease

Bassotti¹,

Germani²,

Pagliaricci

et al. 1998

Dysphagia

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The gastrointestinal tract, and especially the esophagus, is frequently involved in neurological diseases; however, objective studies of gut motor function are few. We carried out an esophageal manometric study in 18 patients with various stages of Parkinson's disease (4 stage I, 4 stage II, 7 stage III, and 3 stage IV) to evaluate the function of the viscus in this disease. Clinical assessment showed that 61% complained of esophageal symptoms such as dysphagia, acid regurgitation, pyrosis, and noncardiac chest pain. Manometric abnormalities were documented also in 61% patients, and were represented by repetitive contractions, simultaneous contractions, reduced LES pressure, and high-amplitude contractions. However, only 33.3% of patients had both symptoms and manometric abnormalities. We conclude that esophageal motor abnormalities are frequent in Parkinson's disease, and may appear at an early stage of the disease.

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Esophageal motor disorders in patients evaluated for dysphagia and/or noncardiac chest pain

Cited by 15 publications

References 38 publications

Esophageal dysfunction in scleroderma. Relationship with disease subsets

Esophageal dysfunction in scleroderma. Relationship with disease subsets

Motility Disorders of the Esophagus

Esophageal Manometric Abnormalities in Parkinson's Disease

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