Esophageal motility disorders

Nelson, James B.; Castell, Donald O.

doi:10.1016/0011-5029(88)90021-1

Cited by 23 publications

(10 citation statements)

References 286 publications

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“…Although dysphagia and heartburn are common symptoms in the presentation of several of the primary esophageal motor disorders [4], the frequency of their coincident presentation (74%) within our sample population was surprising. Objective assessment of 24 patients with both dysphagia and heartburn showed that only 62% exhibited increased acid exposure while 46% actually demonstrated both increased exposure and discernible motility dysfunction.…”

Section: Discussionmentioning

confidence: 93%

Esophageal motility, heartburn, and gastroesophageal reflux: Variations in clinical presentation of esophageal dysphagia

1990

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Dysphagia is a potentially important symptom, often leading to the finding of an anatomical or motility disorder of the esophagus. Dysphagia and heartburn represent two of the most common symptoms associated with esophageal motility disorders. To explore the relationship of symptomatic esophageal dysphagia and heartburn and their association with primary esophageal motor disorders, we have performed a retrospective assessment of 1035 patient evaluations performed at our gastrointestinal laboratory. A clear statistical association of symptomatic dysphagia and heartburn was established; however, no pattern diagnostic of a specific motility disorder was discernible. A sizable fraction of our patient population with dysphagia demonstrated normal esophageal motility. A significant portion of dyspeptic patients exhibited both normal motility and acid exposure. The differences observed between the incidence of subjective symptoms and objective dysfunction may be explained in part by an altered or increased esophageal sensitivity of these patients.

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Section: Discussionmentioning

confidence: 93%

Esophageal motility, heartburn, and gastroesophageal reflux: Variations in clinical presentation of esophageal dysphagia

1990

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“…There is a functional narrowing in the region of the UES. Since the first description by Chevalier Jackson in 1915 and the first series of patients by Kelly in 1919, this disorder has been frequently observed in adult patients, predominantly secondary to neurologic and muscular disorders, previous neck surgery or irradiation, but also as primary idiopathic disorder, especially in advanced age (4)(5)(6). Congenital cricopharyngeal achalasia is a rare condition of unknown etiology, which usually presents with dysphagia, nasopharyngeal reflux during feeding, salivation, and choking in neonates and infants.…”

Section: Introductionmentioning

confidence: 99%

Cricopharyngeal achalasia in connection with autoimmune disorders in a pre-adolescent patient: a case report

2017

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Cricopharyngeal achalasia is an uncommon cause of dysphagia, especially in children. Congenital form is known in neonates and infants. In older children this disease has been reported in very rare cases and mostly in connection with neurological and muscular diseases. We present a case of a 12-year-old girl with a four-year history of dysphagia. Esophagogastroduodenoscopy, radiological contrast swallow study and esophageal manometric study confirmed the diagnosis of cricopharyngeal achalasia. The patient was successfully treated with dilatation of the upper esophageal sphincter. An initial attempt of dilatation appears to be a safe and effective option in the management of cricopharyngeal achalasia in children, and may prevent or at least postpone the need for myotomy. Following the diagnosis of cricopharyngeal achalasia, several autoimmune conditions were diagnosed. Our case report revealed that cricopharyngeal achalasia may occur in association with some other autoimmune conditions, and that autoimmunity may also play a role in cricopharyngeal achalasia itself. IzvlečekKrikofaringealna ahalazija je pri otrocih izjemno redek razlog za disfagijo. Poznana je kongenitalna oblika krikofaringealne ahalazije pri novorojenčkih in dojenčkih, pri starejših otrocih pa so to bolezen doslej opisali zelo redko in večinoma v povezavi z nevrološkimi in mišičnimi boleznimi. V prispevku prikazujemo primer 12-letne deklice s štiriletno anamnezo disfagije. Z ezofagogastroduodenoskopijo, radiološko preiskavo požiranja s kontrastom in ezofagealno manometrijo smo potrdili diagnozo krikofaringealna ahalazija. Bolnico smo uspešno zdravili z dilatacijo zgornjega ezofagealnega ustja. Začetni poizkus zdravljenja z dilatacijo se zdi varna in učinkovita metoda zdravljenja krikofaringelane ahalazije pri otrocih in lahko prepreči ali vsaj odloži potrebo po miotomiji. Po postavitvi diagnoze krikofaringealna ahalazija smo pri bolnici diagnosticirali več avtoimunskih motenj. Opisan primer prikazuje povezavo pojava krikofaringelane ahalazije z avtoimunskim dogajanjem in možnost, da bi lahko bil tudi avtoimunski proces eden od razlogov za pojav krikofaringealne ahalazije.

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“…Ineffective esophageal motility (IEM)/scleroderma esophagus (SE). For the diagnosis of IEM/SE, the readers considered a weak peristaltic activity, enlarged oesophageal lumen, GEJ incontinence with reflux and diminished clearance with delayed cleansing time[5,20,21].…”

mentioning

confidence: 99%

Initial experience with magnetic resonance fluoroscopy in the evaluation of oesophageal motility disorders. Comparison with manometry and barium fluoroscopy

et al. 2006

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The aim of this paper was to assess the diagnostic value of magnetic resonance (MR) fluoroscopy in the study of oesophageal motility disorders and to compare MR fluoroscopy results with those of manometry and barium contrast radiography. Twenty-five subjects referred for dysphagia and three patients in follow-up after pneumatic dilatation of the lower oesophageal sphincter to treat severe achalasia underwent esophageal manometry, barium contrast radiography and MR fluoroscopy. Examinations were performed on a 1.5 T scanner. Dynamic turbo- fast low angle shot (turbo-FLASH) sequences acquired during oral contrast agent administration were used to perform MR fluoroscopy. MR fluoroscopy correctly diagnosed achalasia in nine patients, uncoordination of esophageal body motility in ten and scleroderma oesophagus in one. Diagnostic performance was satisfactory, with a sensitivity of 87.5% and a specificity of 100% in the general depiction of motility alterations. Our work demonstrates that MR fluoroscopic examination in subject affected by oesophageal motility disorders is feasible and can properly depict motility and morphology alterations, achieving correct diagnosis in the majority of cases. Studies on larger populations are necessary to obtain statistically significant results.

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Esophageal motility disorders

Cited by 23 publications

References 286 publications

Esophageal motility, heartburn, and gastroesophageal reflux: Variations in clinical presentation of esophageal dysphagia

Esophageal motility, heartburn, and gastroesophageal reflux: Variations in clinical presentation of esophageal dysphagia

Cricopharyngeal achalasia in connection with autoimmune disorders in a pre-adolescent patient: a case report

Initial experience with magnetic resonance fluoroscopy in the evaluation of oesophageal motility disorders. Comparison with manometry and barium fluoroscopy

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