Esophageal Motility and Gastroesophageal Reflux

Grande, Michele; Villa, Massimo; Cadeddu, Federica

doi:10.5772/29191

Cited by 1 publication

(1 citation statement)

References 31 publications

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“…5,6 Forty to 50% of patients with GERD have abnormal peristaltic activity, while a severe dysmotility is seen in 20%. 7 Currently, no data is available regarding the frequency of esophageal motility disorders (EMD) in patients with GERD is available in Pakistan, hence the aim Esophageal motility disorders in patients with gastro-esophageal reflux disease diagnosed by using high resolution esophageal manometry-data from the developing world of this study was to find out the frequency of esophageal motility disorders in patients with GERD, diagnosed based on Chicago classification by using the High-resolution manometry (HRM). Since environmental, lifestyle factors (like the consumption of tea, coffee, soft drinks, alcohol, spicy food, having a high BMI, smoking) and genetic factors are known risk factors for GERD, its frequency might vary locally depending upon the number of factors that are present.…”

Section: Introductionmentioning

confidence: 99%

Esophageal Motility Disorders in patients with Gastro-Esophageal Reflux Disease diagnosed by using High Resolution Esophageal Manometry- data from the developing world

Majid¹,

Laeeq²,

haq³

et al. 2021

Asian J Med Sci

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Background: Gastro-esophageal reflux disease (GERD) has a prevalence of 10-20% in the Western countries while its prevalence amongst the Pakistani population is between 22 to 24%. Esophageal manometry is currently the gold standard for diagnosing esophageal motility disorders. Aims and Objectives: To determine the frequency of esophageal motility disorder in patients with GERD. Materials and Methods: This cross-sectional study was conducted at the department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan. Patients diagnosed with GERD (defined as having typical reflux symptoms with more than 2 episodes per were) were included in this study. These patients were subjected to upper GI endoscopy followed by esophageal manometry. Esophageal motility disorders were then classificated by using the Chicago classification 3.0. Results: A total of 76 patients were included in our study, out of which 41 (53.9%) were females. A mean age of 46.1 years ± 12 years and a mean body mass index (BMI) of 23.7kg/m2 was noted. The most common comorbid condition seen in our patients was diabetes mellitus, which was seen in 13 patients (17%). A normal EGD was noted in 48 patients (63%). Liquid perfusion esophageal manometer catheter was mainly used in our study that is in 70 patients (92.1%). Weak esophageal peristalsis was the most common esophageal motor abnormality seen in 16 patients (21.1%). Conclusion: A significant proportion of patients with GERD have the presence of a motility disorders, the early identification and treatment of which can lead to improvement GERD symptoms.

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Section: Introductionmentioning

confidence: 99%