Esophageal Impedance Monitoring for Gastroesophageal Reflux

Abstract

Dual pH-multichannel intraluminal impedance (pH-MII) is a sensitive tool for evaluating overall gastroesophageal reflux disease, and particularly for permitting detection of nonacid reflux events. pH-MII technology is especially useful in the postprandial period or at other times when gastric contents are nonacidic. pH-MII was recently recognized by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition as being superior to pH monitoring alone for evaluation of the temporal relation between symptoms and gastroesophageal reflux. In children, pHMII is useful to correlate symptoms with reflux (particularly nonacid reflux), to quantify reflux during tube feedings and the postprandial period, and to assess efficacy of antireflux therapy. This clinical review is simply an evidence-based overview addressing the indications, limitations, and recommended protocol for the clinical use of pH-MII in children.

Çocuklarda Gastroözofagiyal Reflü Hastalığı

“…Ancak maliyeti yüksek olup kullanımı sınırlıdır, verilerin yorumlanması konusunda kanıta dayalı veriler henüz yoktur (1,6,(18)(19)(20)(21). Endoskopi ve biyopsi Özofagus mukozasının görülmesi, hem de biyopsi alınarak histopatolojik olarak değerlendirilebilmesi açısından son derece değerlidir.…”

Evaluation of antireflux surgery using multichannel intraluminal impedance-pH measurement in neurologically impaired patients

“…It can also accurately detect the height of the refluxate. Moreover, it is able to determine whether the refluxate is a liquid, gas or mixture (both liquid and gas) [9,10].…”

Updates on Management of GERD Disease

“…The Mii-pH-24 hour is the study of the refluxes by the Multichannel intra-luminal impedance (Mii), a catheter-based method to detect intra-luminal bolus movement within the esophagus [20]. Mii is performed in combination with manometry or pH testing.…”