Esophageal Disorders

and, Peter J Kahrilas; Hirano, Ikuo

doi:10.1002/9780470760307.ch9

Cited by 1 publication

(1 citation statement)

References 108 publications

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“…In the presence of heartburn and regurgitation, clinical guidelines recommend GERD to be diagnosed as a symptomatic disease and to start antisecretory treatment with proton pump inhibitors (PPI) [8,9]. Regarding the amount of patients, this is also a pragmatic way of disease management and to prevent an overload of healthcare systems.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic Investigations of Gastroesophageal Reflux Disease: Who and When to Refer and for What Test

2018

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Background: Due to the high prevalence and incidence of patients with gastroesophageal reflux disease (GERD), the diagnostic workup of patients with symptoms of GERD needs to be balanced between empiric antisecretory therapy and further functional assessment including endoscopy and reflux monitoring. Methods: This article is based on a literature review (PubMed, Medline) using the terms ‘gastroesophageal reflux disease' or ‘GERD' and ‘diagnosis', ‘therapy', or ‘PPI' with special and critical analysis of the current ‘Porto' consensus report. Results and Conclusions: Further diagnostics are mandatory in case of alarm symptoms as well as atypical or persistent symptoms under adequate therapy with proton pump inhibitors (PPI). In general, the clinical situation needs to be clarified before sending the patients for reflux monitoring. The question is not only when and whom to test but also how to test: on or off PPI therapy, pH-metry, or combined pH-impedance analysis. These questions have been defined in a recent consensus report of an international panel of experts and are further discussed in this article.

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Section: Introductionmentioning

confidence: 99%