Esophageal cancer: pneumo-64-MDCT

Ulla, Marina; Cavadas, Demetrio; Muñoz, I. Pérez; Beskow, Axel; Seehaus, Alberto; García-Mónaco, Ricardo

doi:10.1007/s00261-009-9554-3

Cited by 13 publications

(11 citation statements)

References 22 publications

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“…With this protocol, we achieved a very high sensitivity of 95%, a PPV of 96%, and a good accuracy (76% for reader 1 and 68% for reader 2). The optimal arterial enhancement, the absence of section misregistration artefacts, the use of thin sections and highquality MPRs, and the lumen distension of the oesophagus account for these encouraging results [29][30][31][32][33][34]45]. Moreover, inter-reader variation was low, indicating good diagnostic reproducibility of the technique when combined with our suggested CT staging criteria.…”

Section: Discussionmentioning

confidence: 53%

“…By performing arterial phase contrast-enhanced MDCT, and employing water and gas-producing effervescent granules as negative contrast agents as well as prone positioning, we were able to significantly improve the delineation of the oesophagus and gastro-oesophageal junction, thereby overcoming a number of limitations of prior CT techniques [31][32][33]. With this protocol, we achieved a very high sensitivity of 95%, a PPV of 96%, and a good accuracy (76% for reader 1 and 68% for reader 2).…”

Section: Discussionmentioning

confidence: 98%

“…Recently, Umeoka et al reported that arterial phase MDCT can improve the detection and T staging of oesophageal cancer [29,30]. To further improve this technique, we designed this study combining the arterial phase MDCT technique with consistent distension of the stomach and the oesophagus using water-filling and gas-producing effervescent granules [31][32][33][34][35]. We further applied modified criteria for T staging, based on the literature and our own experience [21, 22, 24-26, 30, 36-38].…”

Section: Introductionmentioning

confidence: 96%

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Accuracy of hydro-multidetector row CT in the local T staging of oesophageal cancer compared to postoperative histopathological results

et al. 2011

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Section: Discussionmentioning

confidence: 53%

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 96%

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Accuracy of hydro-multidetector row CT in the local T staging of oesophageal cancer compared to postoperative histopathological results

et al. 2011

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“…In order to optimize tumor visualization in the esophageal wall and in the GE junction and to give information to the surgeon for the surgical approach, we developed a technique named pneumo-64-MDCT (Pn64MDCT) [24].…”

Section: Techniquementioning

confidence: 99%

Esophageal cancer characterization with pneumo-64-MDCT

et al. 2011

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Early diagnosis and accurate staging of esophageal cancer are both essential for therapeutic strategy planning. Endoscopic ultrasound, CT, and positron emission tomography have all been used in the preoperative staging of esophageal cancer separately or in various combinations. Each imaging method has its strengths and weaknesses. Depiction of the tumor's anatomic location conditions the surgical strategy. Endoscopic ultrasound and PET have important advantages but neither provides information for surgical planning. CT scans have some limitations for hollow organ assessment in the absence of lumen distension, since the organ wall may be collapsed. Therefore, optimal esophageal distension could be very useful to overcome these limitations. This potential drawback is crucial at the level of the GE junction, a typically difficult region to evaluate. In order to optimize tumor visualization in the esophageal wall and in the GE junction, we developed a technique named pneumo-64-MDCT. We achieve maximum lumen distension, which better highlights the thickened areas in relation to the normal esophageal wall. At the present time, we have performed 200 studies with this technique and it proved useful, safe and accurate to identify esophageal wall thickening and to stage esophageal cancer. The additional stomach distension led to an adequate definition of both the upper and lower borders of the lesion in tumors located in the GE junction, which in turn was helpful to design the surgical approach.

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“…Esophageal adenocarcinoma presents an aggressive behavior and is usually diagnosed in advanced stages. Despite recent advances in diagnosis and treatment, the prognosis remains poor and represents the sixth leading cause of cancer death in the world, with a 5-year survival rate of less than 20% [1, 2].…”

Section: Introductionmentioning

confidence: 99%

Pneumo-PET-CT: Initial Results of This Novel Technique on the Evaluation of Esophageal and Gastric Tumors with Anatomic-Surgical Correlation

Diaz

Ulla

Lastiri

et al. 2019

Gastroenterology Research and Practice

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We present the initial results of a novel hybrid scanning-based technique that combines pneumo-computed tomography (PNCT) with positron emission tomography (PET) using 2-(fluorine-18) fluoro-2-deoxy-D-glucose (FDG). We denominate it pneumo-PET-CT. The focus of our discussion will be on the description of the pneumo-PET-CT technique and the interpretation criteria with emphasis on its benefits and applications in the presurgical and postneoadjuvant therapy evaluation of esophageal, esophagogastric junction (EGJ), and gastric tumors.

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Esophageal cancer: pneumo-64-MDCT

Cited by 13 publications

References 22 publications

Accuracy of hydro-multidetector row CT in the local T staging of oesophageal cancer compared to postoperative histopathological results

Accuracy of hydro-multidetector row CT in the local T staging of oesophageal cancer compared to postoperative histopathological results

Esophageal cancer characterization with pneumo-64-MDCT

Pneumo-PET-CT: Initial Results of This Novel Technique on the Evaluation of Esophageal and Gastric Tumors with Anatomic-Surgical Correlation

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