Esophageal cancer complicated by cytomegalovirus esophagitis during chemoradiotherapy: case report

Cytomegalovirus infection of the upper gastrointestinal tract: a clinical and pathological study of 30 cases

“…Contrary to previous reports that underlined the rare involvement of the esophagus in immunocompetent subjects [13,[16][17][18], our study evidenced the occurrence of HCMV infection of the esophagus in a similar number of apparently nonimmunocompromised patients (5/15) and apparently immunocompromised (4/15) ones. Furthermore, the esophagus does not appear to represent the most common site of UGI tract involvement in immunocompromised patients, as previously reported by other authors [2,[13][14][15][16]19], as in our cases the antropyloric area was the most frequently affected region in both apparently immunocompromised and apparently nonimmunocompromised subjects.…”

“…Furthermore, the esophagus does not appear to represent the most common site of UGI tract involvement in immunocompromised patients, as previously reported by other authors [2,[13][14][15][16]19], as in our cases the antropyloric area was the most frequently affected region in both apparently immunocompromised and apparently nonimmunocompromised subjects. Of interest, the involvement of multiple UGI tract organs or of multiple sites of the same organ was detected predominantly in apparently immunocompromised patients (8/15, i.e., 53.3%), when compared with apparently nonimmunocompromised subjects (1/15, i.e., 6.6%), such as all HIV+ cases and patients with previous histories of malignancy and chemotherapy treatment.…”

“…Apart from nonspecific inflammatory changes, such as increased fragility, hyperemia and/or frank erythema, ulcers or erosions represent the most frequently detected endoscopic changes in UGI infected by HCMV [2,11,16,20,21]. In our study, ulcers were observed in 18/30 patients (60%), being single in 10 cases and multiple in 8, and appeared to be localized mainly in the distal portion of the esophagus and in the antropyloric region.…”

Gastroduodenal Ulceration Associated with Radioembolization for the Treatment of Hepatic Tumors: An Institutional Experience and Review of the Literature

“…This is particularly important in a population of oncology patients who may be immunocompromised. Interestingly, one patient in our series and a patient reported by Thamboo et al [45] were found to have cytomegalovirus, a recognized pathogen of the immune-suppressed gastrointestinal tract, in their gastric biopsies [50][51][52].…”

Cytomegalovirus esophagitis developing during chemoradiotherapy for esophageal cancer: two case reports

“…CMV esophagitis is a rare complication of chemoradiotherapy-induced myelosuppression, and is most commonly observed in patients who have undergone stem cell transplantation. Few reports in the literature appear to have described CMV infection of the GIT developing during chemoradiotherapy in patients with solid tumors [ 5 ].…”