Esophageal actinomycosis in a patient with end‐stage renal disease

Abstract

Actinomycosis of esophagus is uncommon. Herpes simplex virus, cytomegalovirus, candidiasis, tuberculosis, and other fungal infections are the commonly reported infections in both immunocompromised and immunocompetent patients. We report a case of esophageal actinomycosis in an end-stage renal disease patient. A 28-year-old lady, known case of systemic lupus erythematosus, hepatitis B virus infection with end-stage renal disease on regular maintenance hemodialysis since 5 years presented with history of epigastric pain and odynophagia for 1 week. Her upper gastrointestinal endoscopic examination revealed extensive necrotic areas with membrane in the esophagus. Histopathology revealed actinomycotic colonies and bacterial clumps. She was treated with intravenous penicillin followed by oral ampicillin for 6 months. She showed marked clinical improvement, and repeat endoscopy showed healing of ulceration and no evidence of actinomycosis.

Esophagitis Due to Actinomycosis in an Immunocompetent Patient with a History of SARS-Cov-2 Infection: Case Report

“…Esophageal epithelium with bacilliform structures consistent with actinomyces. Open Journal of Gastroenterology in the literature, according to the reviews of Murchan et al [5] and Abdalla et al [6] of them, nine were in patients with HIV infection; A new review of cases was carried out after what this article reported, finding 12 more cases of esophageal actinomycosis in patients with end-stage chronic kidney disease [7], non-small cell lung neoplasia (with a history of mediastinal radiation) [8], bronchogenic carcinoma [9], tracheal carcinoma [10], hematological malignancy [11], kidney transplant [12], diabetes [13], eosinophilic esophagitis [14], and immunocompetent [15] [16] [17], but no other cases in patients with HIV infection. but no other cases in patients with HIV infection.…”

Esophageal Actinomycosis Presenting as an Obstructive Esophageal Mass

“…Nagaraju et al described a case of EA in a 28‐year‐old woman with end‐stage renal disease on regular hemodialysis. 9 The endoscopic description of the EA lesion showed extensive esophageal necrotic areas.…”

A rare case of Actinomyces skin and soft tissue infection in an end‐stage kidney disease patient with a review of the literature

“…Treatments were heterogeneous as well, including surgical debridement and oral, intravenous and intraperitoneal antibiotics. Only 1 of 20 reported cases resulted in death 21‐39 …”