EslB is required for cell wall biosynthesis and modification in<i>Listeria monocytogenes</i>

Rismondo, Jeanine; Yacoub, Maria; Wadhawan, Ashima; Dionne, Marc S.; Gründling, Angelika

doi:10.1101/2020.02.03.932061

2020

DOI: 10.1101/2020.02.03.932061

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EslB is required for cell wall biosynthesis and modification inListeria monocytogenes

Jeanine Rismondo

Maria Yacoub

Ashima Wadhawan

et al.

Abstract: 20Lysozyme is an enzyme found in secretions including tears, saliva and mucus and is an 21 important component of the innate immune system. It functions by hydrolysing the 22

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Not Just Transporters: Alternative Functions of ABC Transporters in Bacillus subtilis and Listeria monocytogenes

Rismondo

Schulz

2021

Microorganisms

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ATP-binding cassette (ABC) transporters are usually involved in the translocation of their cognate substrates, which is driven by ATP hydrolysis. Typically, these transporters are required for the import or export of a wide range of substrates such as sugars, ions and complex organic molecules. ABC exporters can also be involved in the export of toxic compounds such as antibiotics. However, recent studies revealed alternative detoxification mechanisms of ABC transporters. For instance, the ABC transporter BceAB of Bacillus subtilis seems to confer resistance to bacitracin via target protection. In addition, several transporters with functions other than substrate export or import have been identified in the past. Here, we provide an overview of recent findings on ABC transporters of the Gram-positive organisms B. subtilis and Listeria monocytogenes with transport or regulatory functions affecting antibiotic resistance, cell wall biosynthesis, cell division and sporulation.

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Not Just Transporters: Alternative Functions of ABC Transporters in Bacillus subtilis and Listeria monocytogenes

Rismondo

Schulz

2021

Microorganisms

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EslB is required for cell wall biosynthesis and modification inListeria monocytogenes

Abstract: 20Lysozyme is an enzyme found in secretions including tears, saliva and mucus and is an 21 important component of the innate immune system. It functions by hydrolysing the 22

Cited by 1 publication

References 55 publications

Not Just Transporters: Alternative Functions of ABC Transporters in Bacillus subtilis and Listeria monocytogenes

Not Just Transporters: Alternative Functions of ABC Transporters in Bacillus subtilis and Listeria monocytogenes

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