Esenbeckia (Pilocarpinae, Rutaceae): chemical constituents and biological activities

Carvalho, Juliana Cajado Souza; Pirani, José Rubens; Ferreira, Marcelo J. P.

doi:10.1007/s40415-021-00747-3

Cited by 4 publications

(2 citation statements)

References 69 publications

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“…Genetic alterations can be related to chemical diversity in many lineages, and Sapindales are particularly rich in natural products, containing many compounds with medicinal properties. Cytotoxic, antiplasmodial, leishmanicidal, larvicidal, antimicrobial and anti-inflammatory properties have been demonstrated in compounds, fractions and extracts of Esenbeckia Kunth (Rutaceae; Carvalho et al 2022). In this review, the authors gathered data on 180 compounds distributed into alkaloids, phenolic derivatives (mostly coumarins and flavonoids), steroids and terpenoids previously identified in species of the genus.…”

Section: Contributions Of the Special Issuementioning

confidence: 99%

Editorial: Diversity and evolution of Neotropical Sapindales

2022

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Section: Contributions Of the Special Issuementioning

confidence: 99%

Editorial: Diversity and evolution of Neotropical Sapindales

2022

Self Cite

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“…Medicinal plants are those which have been utilized throughout human history for the treatment of different diseases. The Rutaceae plants contain a wide range of chemicals and unique pharmacologically active compounds which can be used for various biological and medicinal purposes (Chung S. K., 2000; Carvalho et al, 2022). Available research articles demonstrated that Rutaceae family plants contain a lot of bioactive phytochemicals which can perform antimicrobial, antioxidant, antitumor, and cytotoxic properties (Bocco et al, 1998;Palasuwan et al, 2005;Anmol et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

Isolation and Characterization of Chemical Compounds from the Stem Bark Fractions of Citrus Grandis and Evaluation of Their Antimicrobial, Cytotoxic, and Antioxidant Activities

Sakib,

Mahmud,

Karim

et al. 2023

Bioresearch Communications

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Citrus grandis belongs to the Rutaceae family and is a naturally occurring citrus plant. The fractionated crude extracts of C. grandis have been studied for the investigation of its phytochemicals and allowed for the evaluation of biological activities, especially antimicrobial, cytotoxic, and antioxidant activities. At first, we assessed the antibacterial and antifungal properties using the disc diffusion method and conducted cytotoxicity screening using the brine shrimp lethality bioassay. Among the raw extracts, we isolated two compounds named CG-F3-B1 and CG-F3-B2 through column chromatographic separation of the chloroform extract. By comparing their proton NMR spectra with published spectra, we identified the chemical structures of these compounds as Zeylenol and Limonin, respectively. Regarding antibacterial testing, we observed that the methanol soluble fractions and petroleum ether fractions exhibited mild to moderate activity against bacteria. Additionally, the ethyl acetate soluble fraction showed moderate antibacterial activity. In addition, the crude extract displayed moderate antifungal activity against specific fungi. Furthermore, the cytotoxic assay revealed a relevant cytotoxic effect of a crude extract with an LC50 value of 37 μg/ml. The antioxidant activity was determined using the DPPH assay, and the methanol soluble extract exhibited modest antioxidant activity with an IC50 value of 89 μg/ml. Our findings demonstrated that the stem bark fractions and isolated compounds from C. grandis exhibited various promising biological activities, including antibacterial, antifungal, cytotoxic, and antioxidant properties. Bioresearch Commu. 9(2): 1320-1329, 2023 (July)

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Molecular mechanism of ion channel protein TMEM16A regulated by natural product of narirutin for lung cancer adjuvant treatment

Shi

Bai

et al. 2022

International Journal of Biological Macromolecules

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Esenbeckia (Pilocarpinae, Rutaceae): chemical constituents and biological activities

Cited by 4 publications

References 69 publications

Editorial: Diversity and evolution of Neotropical Sapindales

Editorial: Diversity and evolution of Neotropical Sapindales

Isolation and Characterization of Chemical Compounds from the Stem Bark Fractions of Citrus Grandis and Evaluation of Their Antimicrobial, Cytotoxic, and Antioxidant Activities

Molecular mechanism of ion channel protein TMEM16A regulated by natural product of narirutin for lung cancer adjuvant treatment

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