ESEN: a comparison of vaccination programmes – Part three : measles  mumps and rubella

Lévy-Brühl, Daniel; Pebody, Richard; Veldhuijzen, Irene; Valenciano, Marta; Osborne, K

doi:10.2807/esm.03.12.00112-en

Cited by 25 publications

(20 citation statements)

References 4 publications

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“…mass campaigns in the United Kingdom and the Americas, multidose regimes in the United States and Scandinavia), several authors [9][10][11][12] have stressed the need for all EU countries to increase coverage to target levels of 95 % as recommended in the ' Health for all in the year 2000 ' programme of WHO Europe. The epidemic we have reported is therefore further evidence that vaccination levels of 70-75 % are insufficient to prevent outbreaks, especially in school settings.…”

Section: Discussionmentioning

confidence: 99%

Estimation of the basic reproduction number of measles during an outbreak in a partially vaccinated population

Mossong

2000

Epidemiol. Infect.

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From March to July 1996 a measles outbreak occurred in northern Luxembourg with 110 reported cases centered around two primary schools (85 cases) and the surrounding community (25 cases). Eighty four suspected cases were confirmed serologically. Vaccine coverage was estimated from questionnaire-based surveys at the two primary schools to be 70 and 76%, respectively. Vaccine efficacy during the outbreak was estimated to be 94.6% [95% confidence interval (CI) 90·4–97·0]. Using the information from the school surveys, we obtained estimates of the basic reproduction number of measles of 7·7 (95% CI 4·4–11·0) and 6·2 (95% CI 3·5–8·9), respectively. Assuming a 95% vaccine efficacy, these estimates correspond to minimal vaccine coverages of 91·6% (95% CI 81·4–95·7) and 88·3% (95% CI 75·5–93·4) which would have been necessary to minimize the chances of a major outbreak occurring. We can confirm that major outbreaks in similar school settings can only be prevented if vaccination coverage exceeds 90%.

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Section: Discussionmentioning

confidence: 99%

Estimation of the basic reproduction number of measles during an outbreak in a partially vaccinated population

Mossong

2000

Epidemiol. Infect.

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“…These discrepancies in incidence of disease between countries with similar vaccine coverage may be due to different histories of immunization programmes. However, the use of surveillance data for either setting targets or to compare disease epidemiology between different countries is fraught with difficulties [11]. For example, in France, unlike other countries, the mumps incidence data is extrapolated to account for the incompleteness of mumps notifications [34].…”

Section: Discussionmentioning

confidence: 99%

“…Some of these results have previously been reported [11]. On the basis of mean reported vaccine coverage for mumps vaccine in the 3 years prior to the collection of the main serum banks, countries were divided into high (vaccine coverage >90%), medium (vaccine coverage 80-90%) and low coverage countries (<80 %).…”

Section: Vaccine Programme Structure and Coveragementioning

confidence: 99%

Sero-epidemiology of mumps in western Europe

Nardone¹,

Pebody²,

Hof

et al. 2003

Epidemiol. Infect.

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SUMMARYSix countries (Denmark, England and Wales, France, Germany, Italy and the Netherlands) conducted large serological surveys for mumps, in the mid-1990s, as part of the European Sero-Epidemiology Network (ESEN). The assay results were standardized and related to the schedules and coverage of the immunization programmes and the reported incidence of mumps. Low incidence of disease and few susceptibles amongst adolescents and young adults was observed in countries with high mumps vaccine coverage (e.g. the Netherlands). High disease incidence and large proportions of mumps virus antibody negative samples in adolescent and young adult age groups was noted in countries with poor vaccine coverage (e.g. Italy). The build-up of susceptibles in older children and adolescents in England and Wales, France, the former West Germany and Italy indicate the possibility of further mumps outbreaks in secondary school environments. To control mumps in western Europe, current MMR immunization programmes will need to be strengthened in a number of countries. Sero-surveillance of mumps is an important component of disease control and its usefulness will be enhanced by the development of an international mumps standard.

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“…The disease usually occurs among children and in the prevaccine era, the annual reported mumps incidences in Western European countries ranged between 100 and 600 per 100,000 inhabitants [3]. With the availability of a live-attenuated mumps vaccine since the 1960s [4], disease incidence dramatically decreased in countries with mumps vaccination programmes [5,6].…”

Section: Introductionmentioning

confidence: 99%

Mumps epidemiology in Germany 2007-11

Takla

Wichmann

Klinc³

et al. 2013

Eurosurveillance

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In Germany, mumps has been notifiable until 2013 only in the five Eastern federal states (EFS) of former East Germany. Due to different immunisation policies until 1990 and varying vaccination coverages thereafter, mumps incidences cannot be extrapolated to the 11 Western federal states (WFS). We studied mumps-related International Classification of Diseases (ICD-10) code diagnoses claimed through statutory health insurances between 2007 and 2011 to estimate countrywide mumps incidences in the outpatient sector, and compared them with case numbers from ambulatory notification data. Overall, 32,330 outpatient mumps cases were claimed. Annual incidence ranged between 9.3/100,000 and 11.8/100,000 and showed a significant decreasing trend. Compared with EFS, mumps incidence in WFS was higher and indicated a shift towards older age groups. Notified outpatient case numbers in EFS were 13-fold lower and from voluntary surveillance during an outbreak in the WFS Bavaria 8-fold lower than from insurance data (n=316 versus n=4,217 and n=238 versus 1,995, respectively). Of all notified cases with available information, 75.4% (EFS) and 57.6% (Bavaria) were unvaccinated; 6.8% (EFS) and 19.3% (Bavaria) required hospitalisation. In Germany, mumps is still endemic despite decades of vaccination, with considerable underreporting in the established notification systems.

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ESEN: a comparison of vaccination programmes – Part three : measles mumps and rubella

Abstract: Cet article est le dernier d’une série de trois articles portant sur la comparaison, dans huit pays (Danemark, Angleterre et Pays de Galles, Finlande, France, Allemagne, Italie, Suède et Pays-Bas), des programmes vaccinaux et de l’impact épidémiologique d

Cited by 25 publications

References 4 publications

Estimation of the basic reproduction number of measles during an outbreak in a partially vaccinated population

Estimation of the basic reproduction number of measles during an outbreak in a partially vaccinated population

Sero-epidemiology of mumps in western Europe

Mumps epidemiology in Germany 2007-11

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