“…Based on these patterns of movement, and common mixed polarity microtubule organization in mammals, it appears that autophagosome transport is dependent on microtubules and retrograde motors, such as dynein (Yang et al, 2013;Holzbaur, 2014, 2016). Endosomes, which also appear to depend on dynein for transport, have been found to traffic bidirectionally in dendrites, as have lysosomes (Satoh et al, Lu et al, 2009 SkpA KD Wong et al, 2013;Das et al, 2017;Nanda et al, 2018 APC KD Kim et al, 2009 Highwire LOF mutant Wang et al, 2013SCF KD Wong et al, 2013 Impaired dendritic pruning Cullin1 KD Wong et al, 2013 Impaired dendritic pruning Roc1a KD Wong et al, 2013 Impaired dendritic pruning Slimb KD Wong et al, 2013 Impaired dendritic pruning Rab5 KD Reduced dendritic arbor Impaired dendritic pruning during pupation Satoh et al, 2008;Zhang et al, 2014 Rab11 KD Reduced dendritic arbor Impaired dendritic pruning during pupation Krämer et al, 2019;Siri et al, 2020 ESCRT complex KD Reduced dendritic arbor Impaired dendritic pruning during pupation Zhang et al, 2014;Firkowska et al, 2019HRD1 KD Saldate et al, 2018 Nedd4 KO Kawabe et al, 2010 Atg7 KD in microglia Kim et al, 2017 Only proteins that directly affect dendritic arbor morphology are listed, in the order found in the text. 2008;Jin et al, 2018;Yap et al, 2018).…”