Eschatology

Cole, Graham

doi:10.5040/9780567677273.ch-042

Cited by 3 publications

(3 citation statements)

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“…Obesity was defined as a BMI at or above the 95th percentile of the British 1990 population growth reference ( Cole et al, 1995 ). The Sitar package in R was used to classify the study population as either with obesity or without obesity ( Cole and Cole, 2021 ).…”

Section: Methodsmentioning

confidence: 99%

Molecular mediators of the association between child obesity and mental health

Handakas

Segal

et al. 2022

Front. Genet.

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Biological mechanisms underlying the association between obesity and depression remain unclear. We investigated the role of metabolites and DNA methylation as mediators of the relationship between childhood obesity and subsequent poor mental health in the English Avon Longitudinal Study of Parents and Children. Obesity was defined according to United Kingdom Growth charts at age 7 years and mental health through the Short Mood and Feelings Questionnaire (SMFQ) completed at age 11 years. Metabolites and DNA methylation were measured by nuclear magnetic resonance spectroscopy and Illumina array in blood at the age of 7 years. The associations between obesity and SMFQ score, as continuous count data or using cut-offs to define depressive symptoms (SMFQ >7) or depression (SMFQ >11), were tested using adjusted Poisson and logistic regression. Candidate metabolite mediators were identified through metabolome-wide association scans for obesity and SMFQ score, correcting for false-discovery rate. Candidate DNA methylation mediators were identified through testing the association of putative BMI-associated CpG sites with SMFQ scores, correcting for look-up false-discovery rate. Mediation by candidate molecular markers was tested. Two-sample Mendelian randomization (MR) analyses were additionally applied to test causal associations of metabolites with depression in independent adult samples. 4,018 and 768 children were included for metabolomics and epigenetics analyses, respectively. Obesity at 7 years was associated with a 14% increase in SMFQ score (95% CI: 1.04, 1.25) and greater odds of depression (OR: 1.46 (95% CI: 0.78, 2.38) at 11 years. Natural indirect effects (mediating pathways) between obesity and depression for tyrosine, leucine and conjugated linoleic acid were 1.06 (95% CI: 1.00, 1.13, proportion mediated (PM): 15%), 1.04 (95% CI: 0.99, 1.10, PM: 9.6%) and 1.06 (95% CI: 1.00, 1.12, PM: 13.9%) respectively. In MR analysis, one unit increase in tyrosine was associated with 0.13 higher log odds of depression (p = 0.1). Methylation at cg17128312, located in the FBXW9 gene, had a natural indirect effect of 1.05 (95% CI: 1.01,1.13, PM: 27%) as a mediator of obesity and SMFQ score. Potential biologically plausible mechanisms involving these identified molecular features include neurotransmitter regulation, inflammation, and gut microbiome modulation. These results require replication in further observational and mechanistic studies.

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Section: Methodsmentioning

confidence: 99%

Molecular mediators of the association between child obesity and mental health

Handakas

Segal

et al. 2022

Front. Genet.

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“…Fraudsters often create these elaborate scams to steal the target's sensitive and financial information and/or money launder through the target. 30 Overall, research indicates offenders successfully SE online fraud attacks with linguistic cues of urgency (e.g., 'ASAP'), authority (e.g., 'trust me') and delay (e.g., 'wait') approach. 31 Specific to offenders' attacks on non-offending victims, Akins and Huang's research suggests that 71% of fraudsters used urgency cues to defraud their targets, while 100% of them used authority cues to convince the target of their legitimacy.…”

Section: Online Fraudmentioning

confidence: 99%

Do Offenders [Fraudsters] ‘Collaborate and Listen’? A Quantitative Analysis of Fraudsters’ Decision-making Processes on Active Cybercrime Marketplaces

Cole¹,

Miller

2023

Journal of Victimology and Victim Justice

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Research suggests that an offender–victim overlap within the physical and online environment exists. Therefore, it is unsurprising that online fraudsters have victimized each other (i.e., offender-victims) online. However, research is limited regarding the influence that the situational environment (e.g., online and cyberspace) has on online offender [fraudster] decision-making processes and their interactions with other online offenders. The current study uses criminological and communications theories to explore the influence of the situational environment on offenders’ interactions within illicit online marketplaces. A series of bivariate analyses were run to examine the relationship between the independent variables and the three dependent variables. Then, a series of negative binomial regression models were used to estimate the relationship between the dependent and independent variables. The findings suggest a positive correlation between messages from fraudsters and offender victims and emphasize the role individuals’ socially engineered (e.g., deceptive and manipulative) interactions impact targets, including offender victims.

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“…Thus, the tenants of global health are important to understand. Concepts such as imperialism, 13 neo-colonialism, 14 15 the White Savior Industrial Complex, 16 17 and “good intentions” 18 19 are worthy of pre-trip journal club discussions. These concepts explore some of the ways in which our actions can unintentionally perpetuate disparities, discrimination, and power differentials.…”

Section: Defining Culturementioning

confidence: 99%

Cultural Sensitivity and Ethical Considerations

Bobel

Hinai

Roslani

2022

Clin Colon Rectal Surg

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Global surgery is a burgeoning area of global health. Surgeons can engage in one–or many–of the facets of global healthcare delivery: clinical care, capacity building, education, research, etc. Working in an increasingly global community, surgeons must be aware of the richness of cultural diversity at home and around the world such that they can provide culturally sensitive care. This chapter focuses on the most common way in which surgeons engage in global surgery: surgical short-term experiences in global health (STEGHs). Surgical STEGHs pose an intricate set of ethical dilemmas. As team leaders, surgeons must understand the community they intend to serve on these trips. Further, they should confirm that everyone who joins them is prepared to deliver care in a culturally sensitive and competent manner. Finally, surgeons must consider potential ethical dilemmas that may arise before, during, and after surgical STEGHs and have strategies to navigate them.

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Eschatology

Cited by 3 publications

References 0 publications

Molecular mediators of the association between child obesity and mental health

Molecular mediators of the association between child obesity and mental health

Do Offenders [Fraudsters] ‘Collaborate and Listen’? A Quantitative Analysis of Fraudsters’ Decision-making Processes on Active Cybercrime Marketplaces

Cultural Sensitivity and Ethical Considerations

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