Erythropoietin inhibits neutrophil extracellular traps formation to ameliorate lung injury in a pneumonia model
Sheng Ye,
Wei Li,
Jinghui Yang
et al.
Abstract:Background: Severe pneumonia is a kind of disease that develops from lung inflammation, and new drugs are still required to treat the same. Erythropoietin (EPO) is widely used to treat anemia in patients. However, there are fewer studies on the role of EPO in neutrophil extracellular trappings (NETs) and pneumonia, and the mechanism is unclear.Objective: To investigate the possible effects of EPO on the formation of NETs and progression of pneumonia.Methods: Mice pneumonia model was induced by tracheal lipopol… Show more
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