Erythrophagocytosis and thrombocytopathy occurring during the course of a Henoch-Schönlein syndrome due to quinine

Creger, William P.; Houseworth, John H.

doi:10.1016/0002-9343(54)90252-1

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2012

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Cited by 11 publications

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“…[2][3][4] Adherence of RBCs to and rosetting around neutrophils have also been reported in PCH. [5] Erythrophagocytosis has been reported sporadically following spider bite, [6] quinine administration, [7] and in hemolytic diseases of the newborn. [8] Erythrophagocytosis by cells other than neutrophils has been reported in acute myeloid leukemia, [9] in blast crisis of chronic myeloid leukemia [10] and occasionally in warm autoimmune hemolytic anemia.…”

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confidence: 99%

Florid Erythrophagocytosis on the Peripheral Smear

Chandrashekar

Soni

2012

J Lab Physicians

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Erythrophagocytosis is a relatively rare observation on blood smears. It has been reported in auto immune hemolytic anemias and sporadically in few other conditions. Here, we report a case of florid erythrophagocytosis with severe anemia following a viral infection in an 18-year-old girl. Her complete blood count (CBC) revealed hemoglobin of 3.6 gm/dl and a hematocrit of 10%. The peripheral smear showed erythrophagocytosis by neutrophils and rosetting of erythrocytes around neutrophils. The direct Coombs test and direct Donath- Landsteiner tests were positive.

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