Erythroderma/exfoliative dermatitis: a synopsis

Sehgal, Virendra; Srivastava, Govind; Sardana, Kabir

doi:10.1111/j.1365-4632.2004.01975.x

Cited by 92 publications

(115 citation statements)

References 89 publications

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“…Erythroderma or exfoliative dermatitis is defined as diffuse erythema and scaling of the skin involving more than 90% of the total body surface area. It is more commonly seen in males, with male to female ratio ranging from 2:1 to 4:1 [5]. The male to female ratio in our study was similar, at 2.4:1.…”

Section: Discussionsupporting

confidence: 66%

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A Clinico-Epidemiological Study of Erythroderma in a Tertiary Care Center in Jharkhand

Jose¹,

Chaudhary²,

Sachan³

et al. 2017

IOSR JDMS

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Section: Discussionsupporting

confidence: 66%

“…The male to female ratio in our study was similar, at 2.4:1. Even though it can affect any age group, average age of onset is from 41 -61 years [5,6]. But in our study, the most commonly affected age group was 21-30 years.…”

Section: Discussionmentioning

confidence: 55%

A Clinico-Epidemiological Study of Erythroderma in a Tertiary Care Center in Jharkhand

Jose¹,

Chaudhary²,

Sachan³

et al. 2017

IOSR JDMS

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“…4 There have been varied mortality rates from Bruno and Grewal 18% to 64% published, though mortality has been reduced, generally because of advances in diagnosis and treatment. 5 Because of the extensive rash, fever, fatigue and potential for lymphadenopathy and weight loss, the presentation of erythroderma can masquerade as, or be a manifestation of, more sinister conditions including lymphoma (Sézary syndrome). Indeed, erythroderma may be a presentation of reticuloendothelial or intravascular neoplasms, so it is incumbent on the physician to perform a thorough investigation.…”

Section: Discussionmentioning

confidence: 99%

Erythroderma: a dermatologic emergency

Bruno

Grewal

2009

CJEM

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Erythroderma is a potentially fatal dermatologic emergency that is often mistaken for infection. Indeed, the fact that it is difficult to diagnosis is the main contributor to its significant mortality rate, as treatment is readily available. We present a case of a 36-year-old man who was incorrectly diagnosed and treated for 2 months. We review the etiologies, initial work-up and management of this disease. In our case, the patient was ill, had lost 11.3 kg and developed systemic inflammatory response syndrome. Without proper treatment he was at risk of developing full-blown sepsis. Although there are many causes of erythroderma, prompt initial treatment directed at the underlying etiology typically results in a rapid remission. RÉSUMÉL'érythrodermie constitue une urgence dermatologique potentiellement fatale qui peut souvent être confondue avec une infection. De fait, on attribue principalement l'important taux de mortalité associé à la maladie au fait qu'elle est difficile à diagnostiquer, alors qu'en soi, elle se traite facilement. Nous présentons ici le cas d'un homme de 36 ans qui a reçu un traitement inadéquat pendant deux mois pour un diagnostic erroné. Nous passons en revue les étiologies, les analyses et la prise en charge initiales de cette maladie. Dans ce cas-ci, le patient était mal en point, il avait perdu 11,3 kg et présentait un syndrome de réponse inflammatoire systémique. Faute de traitement approprié, il se trouvait exposé à un risque de sepsis avéré. Bien qu'il y ait de nombreuses causes de l'érythrodermie, un traitement initial instauré sans délai et selon l'étiologie sous-jacente procure généralement une rémission rapide.(e.g., cutaneous T-cell lymphoma and paraneoplastic phenomena), pre-existing dermatoses (e.g., atopic dermatitis, psoriasis, seborrheic dermatitis and pityriasis rubra pilaris), drug reactions, bullous disorders and allergic contact dermatitis. In up to 25% of cases, no underlying cause is found, and so it is termed idiopathic erythroderma. 1Erythroderma accounts for 1% of all dermatologic admissions to hospital and is more commonly seen in male patients. The importance of this disease is highlighted by the consequences of losing the cutaneous barrier: those affected are prone to lose heat, water, protein and electrolytes, and they are more susceptible to cutaneous infections.2 The disease can be mistaken as an infectious process and treated as such. The purpose of this case report is to highlight the pertinent clinical findings of erythroderma and its differentiation from infectious or malignant etiologies. CASE REPORTA 36-year-old man presented to our emergency department (ED). His chief complaint was a generalized pruritic rash ongoing for approximately 2 months. He also complained of concomitant fevers, night sweats and generalized malaise. Over the course of the previous 2 months he had seen his general practitioner and been to a walk-in clinic. Both times, he was given diphenhydramine hydrochloride and a topical corticosteroid without much relief. Ten days bef...

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“…Even with an es mated annual incidence of 35 cases per 1,00,000 dermatology outpa ent visits represen ng 1-1.5% of total skin clinic admissions [1][2][3][4] , the exact e ology and overall ma nagement of exfolia ve derma s o en stands challenging. There exists a number of gaps in the understanding of the metabolic eff ects of exfolia ve derma s and its correc on.…”

Section: Introductionmentioning

confidence: 99%