Erythrocyte interactions – Comparison of the aggregation power of polymer molecules used in medicine – Not only size does matter

Abstract

Our results show that molecule's AP is significantly dependent on their chemical nature - i.e. not only molecular size does matter.

Facilitating trehalose entry into hRBCs at 4 °C by alkylated ε-poly(l-lysine) for glycerol-free cryopreservation

“…35,54 In order to achieve a similar effect to PEG, PVP 3500 and PVP 8000 with molecular weights of 3500 and 8000, respectively, were tested, which were comparable to PEG 3350 with molecular sizes of 3-4 nm. 55,56 It was found the result of PVP was consistent with the previous observation of PEG, that the intracellular loading content of trehalose in hRBCs after incubation in the presence of PVP 8000 at 10-30 mM was significantly increased (Fig. 4A).…”