Erythrocyte count and hemoglobin levels in diabetic women

Abstract

Fasting blood glucose, erythrocyte counts hemoglobin levels of 131 Libyan diabetic women of Tripoli , Libya were determined. The respective mean values were 223 +/- 7 mg X dl-1, 4.97 +/- 0.034 X 10(6) X mm-3 and 14.4 +/- 0.127 g X dl-1. Sixty-five percent of these diabetic women were obese. The highest percent of diabetics belong to the age group 46-55 years. The increase in prevalence of diabetes correlates with an increase in obesity. A significant positive correlation was found between body surface area and fasting blood glucose levels (r = 0.65; P less than 0.001). Elevated levels of erythrocyte count and hemoglobin were present in these diabetic patients. Significant correlations were found between body surface area and erythrocyte count, as well as between fasting blood glucose levels and erythrocyte count, indicating the effect of obesity and diabetes on erythrocyte numbers. A significant correlation was found between fasting blood glucose levels and hemoglobin (r = 0.35; P less than 0.001). The elevated levels of hemoglobin present in these patients may be the result of haemoconcentration due to polyuria, which is always present in poorly controlled diabetic patients. The results suggest a close relationship between diabetes and obesity. Regulation of body weight/surface area is an important factor in the control of diabetes. The elevated levels of erythrocyte count and hemoglobin reflect poor control of blood glucose levels in these diabetic patients.

Iron deficiency in early pregnancy using serum ferritin and soluble transferrin receptor concentrations are associated with pregnancy and birth outcomes

“…A notable limitation is the lack of data on maternal anaemia. Data from previous studies suggest that increased haemoglobin is associated with increased risk of glucose intolerance, diabetes and GDM, [40][41][42] and one study which found no difference in the incidence of GDM between anaemic and non-anaemic women found women with ID anaemia had about one-half the incidence of GDM compared with non-anaemic women. 43 The relationship between anaemia and GDM is not well understood and requires further study.…”

Mechanisms of Lower Maintenance Dose of Tacrolimus in Obese Patients

“…25,26,28) Zahir et al have reported that hematocrit and red blood cell count significantly influenced the percentage of tacrolimus associated with erythrocytes and the fraction of unbound tacrolimus was correlated with ¡1-acid glycoprotein and high density lipoprotein cholesterol concentrations. 28) There are several reports suggesting that erythrocyte counts are increased in obese patients compared with non-obese patients, [29][30][31] although no clear effect of obesity on hematocrit has been reported. Moreover, laboratory data provided by the breeder of Zucker rats suggested no significant difference in erythrocyte counts or hematocrit between lean and obese Zucker rats.…”

Erythroid Disturbances Before and After Treatment of Portuguese Psoriasis Vulgaris Patients

“…[11,12] A strong association between psoriasis, overweight obesity, and cardiovascular co-morbidities has been proposed. [13][14][15][16] Obesity is a proinflammatory state, presenting as a low-grade, chronic inflammatory condition that might further enhance inflammation in psoriatic patients; [17,18] it might also stimulate erythropoiesis to increase the number of circulating red cells [19] to face the higher oxygen requirements, due to the increase in body mass.…”