Erythroblastic sarcoma presenting as a unilateral pleural effusion in a patient with myelodysplastic syndrome/myeloproliferative neoplasm—Case report with cytologic and histologic findings

Abstract

Erythroblastic sarcoma (ES) is an extremely rare extramedullary solid tumor of immature erythroid cells, with around a dozen human cases to our knowledge presented so far in the english literature, none of the cases presenting as pleural effusion. Here we describe a case of ES in a thoracic wall diagnosed by cytological examination of pleural effusion with histologic correlation in a 53-year-old patient with a 10month history of myelodysplastic syndrome/myeloproliferative neoplasm with grade III reticulin myelofibrosis.

Erythroblastic sarcoma transformation from a chronic myeloid neoplasm with FGFR1 rearrangement presenting as a pleural effusion: a case report

“…A single case report of erythroblastic sarcoma presenting as a pleural effusion arising in a patient with history of MDS/ MPN was recently reported [16]. In contrast to this recent case report, our patient presented with an isolated pleural effusion without a distinct mass identified by imaging studies.…”