1995
DOI: 10.1111/j.1600-0536.1995.tb00562.x
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Erythema‐multiforme‐like contact dermatitis due to phenylbutazone

Abstract: A 65-year-old woman presented with a severely itchy prethoracal eruption of erythematous, edematous papules and papulovesicles. These were much more pronounced on the right side, with some presternal confluence, and had already been spreading for 3 days. She also had erythematous papules on both inner thighs. A week before the onset, she had applied the revulsive (counterirritant) cream NF V for 4 days to the right side of the thorax for muscle pain, which she stopped when the eruption started. Revulsive cream… Show more

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Cited by 23 publications
(4 citation statements)
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“…Unlike erythema multiforme (EM), the EM‐like contact eruption does not have symmetrically acral distribution or characteristic histology (1, 2), and rarely involves the oral mucosa. In general, it is considered to be an id‐like reaction occurring with powerful sensitization, penetration‐enhancing substances, high concentrations or repeated application of allergens (3, 4). Fisher (5) has reviewed the allergens reported and we have listed recently reported cases in Table 1.…”
Section: Discussionmentioning
confidence: 99%
“…Unlike erythema multiforme (EM), the EM‐like contact eruption does not have symmetrically acral distribution or characteristic histology (1, 2), and rarely involves the oral mucosa. In general, it is considered to be an id‐like reaction occurring with powerful sensitization, penetration‐enhancing substances, high concentrations or repeated application of allergens (3, 4). Fisher (5) has reviewed the allergens reported and we have listed recently reported cases in Table 1.…”
Section: Discussionmentioning
confidence: 99%
“…Eczema can also occur as a secondary phenomenon such as in scabies where it occurs as a reaction to the mites' feces, in phthiriasis, mycoses including candidiasis, and impetiginous infections. On the other hand, rarely ACD can also hide behind non-eczematous lesions such as erythema-multiform-like [13,14], urticarial papular plaques, lichen-planus like and lichenoid eruptions [15], purpuric petechial reactions [16], dermal reactions [17], lymphomatoid contact dermatitis [18], granulomatous and pustular reactions [19] and finally pemphigoid-like lesions [20].…”
Section: Differential Diagnosesmentioning
confidence: 99%
“…Other causative drugs include sulfonamide [27, 28], promethazine [25], neomycin [25], mafenide acetate [29], ethylenediamine [25, 30], and mephenesin [31, 32]. Among nonsteroid anti-inflammatory drugs, phenylbutazone [33], bufexamac [34], and mofebutazone [35] have been reported. Among corticosteroids, budesonide [36] and triamcinolone acetonide [37] caused analogous reactions.…”
Section: Erythema Multiforme-like Contact Dermatitismentioning
confidence: 99%