Erythema gyratum repens: Arzneimittelreaktion nach Azathioprin bei einer Patientin mit Autoimmunhepatitis Typ I

Abstract

This is the first report of an erythema gyratum repens in association with azathioprine treatment in an autoimmune hepatitis type I patient with proven common polymorphism in the TPMT gene.

Erythema gyratum repens‐like eruption occuring in resolving psoriasis during methotrexate therapy

“…The present case is different from the earlier reported cases as our patient never had any clinical or histologic evidence of pustular psoriasis and she was being treated with methotrexate. Although EGR is also known to occur as a drug‐hypersensitivity reaction, 8,9 it is unlikely that methotrexate was the cause in our case, as the eruption subsided despite continuation of the drug at tapered doses.…”

Erythema gyratum repens as a manifestation of drug reaction with eosinophilia and systemic symptoms

“…[7] Erythema gyratum repens has been reported following drugs such as azathioprine and in the resolving stage of pityriasis rubra pilaris. [910] Despite extensive literature search, we did not come across any previous reports of erythema gyratum repens occurring during the treatment of DRESS. Although our patient had rash on the face, trunk, and limbs, erythema gyratum repens pattern spared the face as described in the literature.…”

“…Although our patient had rash on the face, trunk, and limbs, erythema gyratum repens pattern spared the face as described in the literature. [9]…”

Primary manifestation of erythema gyratum repens as a transient erythroderma in a patient with bronchial carcinoma

“…In 80% of the cases, an underlying neoplasia can be detected 1 . There have also been case reports demonstrating an association with non‐neoplastic diseases, for example, tuberculosis, 1,2 drug use, 3,4 and lupus dermatitis 5,6 …”

“…1,2 In 80% of the cases, an underlying neoplasia can be detected. 1 There have also been case reports demonstrating an association with non-neoplastic diseases, for example, tuberculosis, 1,2 drug use, 3,4 and lupus dermatitis. 5,6 Our patient's initial dermatologic consultation was in March 2005 because of a persistent, generalized erythroderma of nearly 2 months' duration ( Fig.…”