1977
DOI: 10.1159/000250954
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Erythema dyschromicum perstans

Abstract: Four patients with ashy dermatosis are described. Their ages varied from 8 to 12 years. Three had typical widespread macular eruptions and one had a linear lesion not described before. The follow-up investigation revealed that the eruption disappeared within 2 years in three of the patients. One patient could not be followed. The duration of the disease and the linearity of one lesion resembled lichen ruber planus.

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Cited by 21 publications
(7 citation statements)
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“…Two previously described children had lesions oriented along Blaschko lines (2,3). Given the usual orientation and failure to resolve of their lesions, these patients may have had an alternate diagnosis, such as pigment mosaicism or a variant of incontinentia pigmenti.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Two previously described children had lesions oriented along Blaschko lines (2,3). Given the usual orientation and failure to resolve of their lesions, these patients may have had an alternate diagnosis, such as pigment mosaicism or a variant of incontinentia pigmenti.…”
Section: Resultsmentioning
confidence: 99%
“…The diagnosis of EDP is based on the appearance of the symmetric, 0.5-2 cm, ashy gray to blue, hyperpigmented oval plaques and patches. Linear lesions that resembled EDP, but were oriented along Blaschko lines, have been described in two prepubertal patients (2,3). Although the presence of erythema at lesional borders is inconsistent, dermal lymphohistiocytic infiltrates are regularly seen in biopsy sections of the hyperpigmented lesions of EDP, with both CD4 + and CD8 + cells demonstrated by immunoperoxidase staining (33).…”
Section: Discussionmentioning
confidence: 99%
“…They are disseminated and symmetrical, located on the trunk and proximal limbs, and may ex tend to the neck and the face (9,32). In three cases, they had a segmentary distribu tion (9,50); one was comprised of linear le sions on the arm (41). The palms, soles, scalp and mucous membranes are spared.…”
Section: Commentmentioning
confidence: 99%
“…The palms, soles, scalp and mucous membranes are spared. Once developed, the dermatosis is stable but may disappear spontaneously (38,50) or subside within two to three years (27,51,58). Distinctly different clinical forms have been described on the basis of varying hues or particular location of skin lesion.…”
Section: Commentmentioning
confidence: 99%
“…The pathogenesis of pediatric EDP is still obscure, although some cases may be associated with drug intake and viral infection (1,3). Two pediatric cases had lesions following Blaschko’s lines, suggesting the involvement of genetic factors (4,5).…”
mentioning
confidence: 99%