“…Erythema annulare centrifugum of Daricr (1916), by contrast, has been related not only to benign or malignant tumours (Herzberg & Seelemann, 1953;Lazar, 1963;Dupre et al, i979)) but also on occasion to hypersensitivity to Penicillium (Shelley, 1964) or to a dermatophyte (Jillson, 1954). Erythema annulare centrifugum has, furthermore, been documented in association with systemic or chronic LE (Ellis & Friedman, 1954;Irgang, 1957;Rekant & Becker, 1973;Baccareda, 1974;Heid era/., 1977), and may also occur during the course of LE as an adverse reaction to antimalarial therapy (Grupper, 1957;Ashurt, 1967). Neither EGR nor EAC, however, demonstrate the classical histological changes of LE which are found in LEGR.…”