Erythema annulare centrifugum (darier) in anewborn infant

Fried, Ralph I.; Schonberg, Irving L.; Litt, Jerome Z.

doi:10.1016/s0022-3476(57)80014-6

Cited by 30 publications

(9 citation statements)

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“…[26][27][28][29][30] The diagnosis of EAC with neonatal onset was therefore made. 31,32 To our knowledge only one other case with such a long follow up has been published. 33 As in the case reported by Guillet et al the disappearance of skin lesions during the course of febrile episodes strongly suggests an altered regulation of skin inflammation processes by cytokines.…”

Section: Discussionmentioning

confidence: 93%

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Erythema annulare centrifugum: report of a case with neonatal onset

Bottoni

Innocenzi

Bonaccorsi

et al. 2002

Acad Dermatol Venereol

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Darier's erythema annulare centrifugum (EAC) is often associated with infectious, autoimmune or neoplastic disease, nevertheless, most cases of EAC remain unexplained. We report a case of EAC with neonatal onset and a clinical course of over 20 years. The patient presented from the 6th day of life with erythematous papules that enlarged centrifugally to form figurate, annular or policyclic plaques involving the entire cutaneous surface. The clinical picture had a chronic course, disappearing only during unrelated febrile episodes. Histologic examination revealed a normal epidermis and a dense perivascular lymphohistiocytic infiltrate and numerous eosinophils in the superficial and reticular dermis. Today the patient is 24 years old and his lesions are still unchanged. Recently, clinical evaluation revealed a diffuse sderodermic induration. A second biopsy showed a diffuse thickening of collagen fibers in the dermis. To our knowledge, this is the second report of EAC with neonatal onset and such a long and peculiar clinical course.

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Section: Discussionmentioning

confidence: 93%

“…The diagnosis of EAC with neonatal onset was therefore made 31,32 . To our knowledge only one other case with such a long follow up has been published 33 .…”

Section: Discussionmentioning

confidence: 99%

Erythema annulare centrifugum: report of a case with neonatal onset

Bottoni

Innocenzi

Bonaccorsi

et al. 2002

Acad Dermatol Venereol

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“…The deep type presents as recurrent, red, annular lesions with firm, cordlike borders. Lesions are Erythema annulare centrifugum 7,8 Familial annular erythema 9 Erythema chronicum migrans with Lyme disease 10 Eosinophilic cellulitis 3 Erythema gyratum atrophicans transiens neonatale 11,12 Neonatal lupus erythematosus 13,14 Urticaria 4 Neonatal syphilis 4 Erythema multiforme 15 Erythema gyratum repens 5 Figure 5 The eruption on the trunk at 5 years old exhibits an erythema gyratum repens type of pattern, which has occurred on several occasions. non-pruritic and devoid of vesicles or scales.…”

Section: Discussionmentioning

confidence: 99%

“…Both variants can occur in the newborn period. 8,11 Erythema annular centrifugum is suspected to be caused by a hypersensitivity to a dermatophyte, viral or bacterial infection, neoplastic disease, immunological disorder, drug or food. 4 Medium strength topical corticosteroids have been reported to be effective for the superficial variant.…”

Section: Discussionmentioning

confidence: 99%

Congenital annular erythema persisting in a 15‐year‐old girl

2002

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We present a 15-year-old girl who has had a persisting extensive annular erythematous eruption since birth. Otherwise, she is healthy and developmentally normal. Multiple investigations throughout the years have been normal or negative. Numerous treatments have been tried, but with little success. Both clinical and histological examination fit no known classification. It is most consistent with annular erythema of infancy but could be the first reported case of a new entity. A review of other causes of annular erythema in infancy is presented.

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“…Various causes of annular erythematous lesions in the first few weeks of life include neonatal lupus erythematosus (NLE), erythema annulare centrifugum, annular erythema of infancy, familial annular erythema, tinea corporis, acute urticarial and erythema atrophicans transiens neonatal. [2][3][4][5][6][7] …”

Section: Introductionmentioning

confidence: 99%

Annular erythema of infancy: A diagnostic challenge

Saha¹,

Seth²,

Mukherjee³

et al. 2014

Indian J Paediatr Dermatol

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lesions all over body predominantly over the trunk and face since the 2 nd day of life.The mother was a multigravida with history of 2 abortions at 12 and 16 weeks in the past, however the causes for which were not evaluated. She was healthy and asymptomatic. There was no history suggestive of any connective tissue disease.Clinical examination revealed an alert, euglycemic infant weighing 3.2 kg with good reflexes. Cutaneous examination revealed multiple brightly erythematous, annular plaques distributed over the chest, back, arms and thighs including the face [ Figure 1]. The expanding borders of the lesions were palpable, and there was no detectable scaling or atrophy [ Figures 2 and 3]. Individual lesions were persistent and enlarging since their appearance.Considering the clinical examination and history a provisional diagnosis of the annular variant of NLE was considered and investigations were carried out.Routine blood investigations in the child revealed a raised total leucocyte count with the blood culture showing growth of Klebsiella organisms. The mother was evaluated for Antiphospholipid antibody syndrome ABSTRACT Annular erythemas in infancy are uncommon to rare in occurreance. Erythema migrans is the most common variety to be reported amidst the younger age group. This group of conditions poses a diagnostic challenge to the physician as the differentials can range from a benign annular erythema of infancy with good prognosis and no long-term defects to neonatal lupus erythematosus (NLE) having a bad prognosis with increased morbidity and mortality. We report a case of annular erythema of infancy in a 5 day old male infant to emphasize that in spite of the history of spontaneous abortions in the mother, which pointed towards a more grave diagnosis of NLE, benign conditions like annular erythema of infancy needs to be kept in mind.

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Erythema annulare centrifugum (darier) in anewborn infant

Cited by 30 publications

References 1 publication

Erythema annulare centrifugum: report of a case with neonatal onset

Erythema annulare centrifugum: report of a case with neonatal onset

Congenital annular erythema persisting in a 15‐year‐old girl

Annular erythema of infancy: A diagnostic challenge

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