Erysipeloid as an Occupational Disease

Klauder, Joseph V.

doi:10.1001/jama.1938.02790410001001

Cited by 50 publications

(10 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, we cannot rule out the possibility that the detection of E. rhusiopathiae in tissues sampled from older carcasses could be the result of post-mortem bacterial transmigration, wherein bacteria enter tissues after death (Morris et al, 2006), or contamination from the external environment. Anecdotal reports in some of the older literature suggest that E. rhusiopathiae is commonly found in dead and decomposing matter (Klauder, 1938; Shuman, 1970). Longitudinal epidemiological studies that involve targeted surveillance and timely sample collection and testing will be necessary to better understand the role of E. rhusiopathiae in wild ungulate mortalities and investigate what other factors may be contributing, including viral infections, poisoning, and/or environmental stressors.…”

Section: Discussionmentioning

confidence: 99%

Bacterial Genomics Reveal the Complex Epidemiology of an Emerging Pathogen in Arctic and Boreal Ungulates

et al. 2016

View full text Add to dashboard Cite

Northern ecosystems are currently experiencing unprecedented ecological change, largely driven by a rapidly changing climate. Pathogen range expansion, and emergence and altered patterns of infectious disease, are increasingly reported in wildlife at high latitudes. Understanding the causes and consequences of shifting pathogen diversity and host-pathogen interactions in these ecosystems is important for wildlife conservation, and for indigenous populations that depend on wildlife. Among the key questions are whether disease events are associated with endemic or recently introduced pathogens, and whether emerging strains are spreading throughout the region. In this study, we used a phylogenomic approach to address these questions of pathogen endemicity and spread for Erysipelothrix rhusiopathiae, an opportunistic multi-host bacterial pathogen associated with recent mortalities in arctic and boreal ungulate populations in North America. We isolated E. rhusiopathiae from carcasses associated with large-scale die-offs of muskoxen in the Canadian Arctic Archipelago, and from contemporaneous mortality events and/or population declines among muskoxen in northwestern Alaska and caribou and moose in western Canada. Bacterial genomic diversity differed markedly among these locations; minimal divergence was present among isolates from muskoxen in the Canadian Arctic, while in caribou and moose populations, strains from highly divergent clades were isolated from the same location, or even from within a single carcass. These results indicate that mortalities among northern ungulates are not associated with a single emerging strain of E. rhusiopathiae, and that alternate hypotheses need to be explored. Our study illustrates the value and limitations of bacterial genomic data for discriminating between ecological hypotheses of disease emergence, and highlights the importance of studying emerging pathogens within the broader context of environmental and host factors.

show abstract

Section: Discussionmentioning

confidence: 99%

Bacterial Genomics Reveal the Complex Epidemiology of an Emerging Pathogen in Arctic and Boreal Ungulates

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Erysipelothrix spp. are ubiquitous in nature, particularly in the presence of decomposing nitrogenous substances (Klauder, ). They can persist for long periods in aquatic environments and are known to colonize mucosal surfaces in freshwater and marine fish, reptiles, marine mammals and invertebrates (Bauwens, Cnops, & Demeurichy, ; Wang et al., ).…”

Section: Introductionmentioning

confidence: 99%

Characterization of spaC‐type Erysipelothrix sp. isolates causing systemic disease in ornamental fish

Pomaranski

Reichley

Yanong

et al. 2017

Journal of Fish Diseases

View full text Add to dashboard Cite

Since 2012, low-to-moderate mortality associated with an Erysipelothrix sp. bacterium has been reported in ornamental fish. Histological findings have included facial cellulitis, necrotizing dermatitis and myositis, and disseminated coelomitis with abundant intralesional Gram-positive bacterial colonies. Sixteen Erysipelothrix sp. isolates identified phenotypically as E. rhusiopathiae were recovered from diseased cyprinid and characid fish. Similar clinical and histological changes were also observed in zebrafish, Danio rerio, challenged by intracoelomic injection. The Erysipelothrix sp. isolates from ornamental fish were compared phenotypically and genetically to E. rhusiopathiae and E. tonsillarum isolates recovered from aquatic and terrestrial animals from multiple facilities. Results demonstrated that isolates from diseased fish were largely clonal and divergent from E. rhusiopathiae and E. tonsillarum isolates from normal fish skin, marine mammals and terrestrial animals. All ornamental fish isolates were PCR positive for spaC, with marked genetic divergence (<92% similarity at gyrB, <60% similarity by rep-PCR) between the ornamental fish isolates and other Erysipelothrix spp. isolates. This study supports previous work citing the genetic variability of Erysipelothrix spp. spa types and suggests isolates from diseased ornamental fish may represent a genetically distinct species.

show abstract

“…rhusiopathiae was widely distributed on the various seafoods tested, and all fish were positive. It is well recognized that fish are a common source of E. rhusiopathiae (17,21), and infection can be most severe when contracted from a fish (13). E. rhusiopathiae was also isolated from Western rock lobster.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Methods for Detection of Erysipelothrix spp. and Their Distribution in Some Australasian Seafoods

Fidalgo

Wang

Riley

2000

Appl Environ Microbiol

View full text Add to dashboard Cite

For many years, Erysipelothrix rhusiopathiae has been known to be the causative agent of the occupationally related infection erysipeloid. A survey of the distribution of Erysipelothrix spp. in 19 Australasian seafoods was conducted, and methodologies for the detection of Erysipelothrix spp. were evaluated. Twenty-one Erysipelothrix spp. were isolated from 52 seafood parts. Primary isolation of Erysipelothrix spp. was most efficiently achieved with brain heart infusion broth enrichment followed by subculture onto a selective brain heart infusion agar containing kanamycin, neomycin, and vancomycin after 48 h of incubation. Selective tryptic soy broth, with 48 h of incubation, was the best culture method for the detection of Erysipelothrix spp. with PCR. PCR detection was 50% more sensitive than culture. E. rhusiopathiae was isolated from a variety of different fish, cephalopods, and crustaceans, including a Western rock lobster (Panulirus cygnus). There was no significant correlation between the origin of the seafoods tested and the distribution of E. rhusiopathiae. An organism indistinguishable from Erysipelothrix tonsillarum was isolated for the first time from an Australian oyster and a silver bream. Overall, Erysipelothrix spp. were widely distributed in Australasian seafoods, illustrating the potential for erysipeloidlike infections in fishermen.

show abstract

Erysipeloid as an Occupational Disease

Cited by 50 publications

References 2 publications

Bacterial Genomics Reveal the Complex Epidemiology of an Emerging Pathogen in Arctic and Boreal Ungulates

Bacterial Genomics Reveal the Complex Epidemiology of an Emerging Pathogen in Arctic and Boreal Ungulates

Characterization of spaC‐type Erysipelothrix sp. isolates causing systemic disease in ornamental fish

Comparison of Methods for Detection of Erysipelothrix spp. and Their Distribution in Some Australasian Seafoods

Contact Info

Product

Resources

About