Eruptive xanthomas with Koebner phenomenon, type 1 diabetes mellitus, hypertriglyceridaemia and hypertension in a 41-year-old man

Generalized eruptive xanthomas associated with diabetic dyslipidemia

“…Physical examination showed small, generalized, pruritic, yellowish papules on an erythematous base. This patient is particular because of the Koebner phenomenon (its appearance is rarely reported in eruptive xanthomas associated with metabolic syndrome) [4]. Microscopic examination of a biopsy taken from a skin lesion showed grouped foamy cells, with extracellular lipid between collagen bundles dominantly present in the reticular dermis, and a moderate inflammatory infiltrate throughout the dermis (figures 1C-D).…”

“…In 2002, el-Azhary and Pakzad divided ADM into 3 groups and group 2 is also known as hypomyopathic dermatomyositis (HDM) [2]. HDM, a term first reported by Sontheimer in 1999 [3], is characterized by the presence of typical DM skin lesions for 6 months or longer in individuals who have no muscle weakness but who have some evidence of muscle inflammation upon testing (muscle enzyme levels, electromyogram, muscle biopsy, muscle magnetic resonance imaging) [4]. Juvenile DM (JDM) cases manifesting as eruptions along the Blaschko-line have been reported in a few cases [5,6].…”