Eruptive Vellus Hair Cysts

Torchia, Daniele; Vega, Janelle; Schachner, Lawrence A.

doi:10.2165/11589050-000000000-00000

Cited by 39 publications

(81 citation statements)

References 78 publications

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“…Subsequent reports showed that the condition is usually acquired, appearing mostly during the first three decades of life (mean age at diagnosis 24 years) [2], although it may be present at birth [1,2,3]. The development of lesions is usually progressive, but not necessarily eruptive, contrary to what their name suggests.…”

Section: Discussionmentioning

confidence: 99%

“…There is a slight female predominance (1.3:1). Most reported patients were Caucasians, but EVHC also affect Asian and Black people [2]. Typically, EVHC manifest as multiple (2–400) smooth, uniform, grouped or scattered papules or nodules measuring 1–7 mm, occurring symmetrically on the mid-chest, the neck, the extensor or flexor extremities and the axilla.…”

Section: Discussionmentioning

confidence: 99%

“…Typically, EVHC manifest as multiple (2–400) smooth, uniform, grouped or scattered papules or nodules measuring 1–7 mm, occurring symmetrically on the mid-chest, the neck, the extensor or flexor extremities and the axilla. Rare patients with a single lesion or with generalized ones exist [2]. Facial lesions occur [4]; they were the unique localization in ten cases [2] and were unilateral in one of them [5].…”

Section: Discussionmentioning

confidence: 99%

“…Rare patients with a single lesion or with generalized ones exist [2]. Facial lesions occur [4]; they were the unique localization in ten cases [2] and were unilateral in one of them [5]. Unusual sites include the back, labium major [6], the buttocks and groin [7].…”

Section: Discussionmentioning

confidence: 99%

“…They manifest clinically with multiple, small papules with a smooth or centrally umbilicated surface and consist pathologically of epidermoid cysts containing vellus hairs. Up till now 222 cases of EVHC have been published in the literature [2]. We report herein a new case of this uncommon condition studied immunohistochemically in a male adolescent suffering also from juvenile acne.…”

Section: Introductionmentioning

confidence: 99%

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Eruptive Vellus Hair Cysts: Report of a New Case with Immunohistochemical Study and Literature Review

Zaharia

Kanitakis²

2012

Dermatology

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Eruptive vellus hair cysts (EVHC) are rather uncommon lesions, of which 222 cases have been published in the literature. Their etiopathogenesis is poorly known. We report herein a new typical case of EVHC that was studied immunohistochemically. A 15-year-old male presented with a 4-year history of progressively developing small brown-gray papules on the trunk and extremities. Microscopically the lesions consisted of small epidermoid cysts containing vellus hairs. Immunohistochemically, the lesions expressed keratin 1/10, calretinin and p63 but no epithelial membrane antigen, filaggrin or androgen receptors. A review of the relevant literature shows that EVHC may be inherited or acquired and may be associated to other genodermatoses, namely sebocystomatosis. They could be due to hamartomatous follicular growth, to a trouble in infundibular keratinization leading to vellus hair follicle occlusion, or represent an example of acquired hamartoma. Although benign, this condition is difficult to treat.

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