Eruptive vellus hair cysts

Lee, S.

doi:10.1001/archderm.120.9.1191

Cited by 21 publications

(5 citation statements)

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“…The biopsies of the mother’s cysts revealed the typical features of steatocystoma in the biopsy taken from one of the larger cysts located in the trunk and features of EVHC in the biopsy taken from one of the cysts of the face. The association of a sebaceous gland near the cyst, as observed in this case, has previously been described in EVHC [7], but some authors have suggested that cysts with these histopathologic features might be considered ‘hybrid cysts’ with features of both SM and EVHC [8, 9, 10, 11]. …”

Section: Discussionsupporting

confidence: 55%

Persistent Milia, Steatocystoma multiplex and Eruptive Vellus Hair Cysts: Variable Expression of Multiple Pilosebaceous Cysts within an Affected Family

et al. 1998

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Background: Steatocystoma multiplex (SM) and eruptive vellus hair cysts (EVHC) are conditions characterized by numerous cutaneous cysts with a clinical resemblance, such as age of onset, location, appearance of the lesions and mode of inheritance, but with distinctive histologic features. Recently, some authors have proposed that the two conditions are variants of one entity originating in the pilosebaceous duct, while others suggest that SM and EVHC are two distinct entities, on the basis of the different expression of keratins. Milia are small round cysts, commonly involving the face. In 1994, Menni and Piccinno reported the first association, in a family, between persistent infantile milia in a 9-month-old girl and SM in the father. The authors hypothesized a relationship between these two conditions. Objective: We describe a family in which the mother showed cystic lesions and milia and her 4-year-old son and her 18-month-old daughter presented persistant infantile milia. Methods: In addition to the clinical and genetic documentation, a biopsy was performed in the son and two biopsies in the mother. Results: The histologic examination of one of the son’s milium-like papules showed in the superficial dermis a small cyst typical of a milium. In serial sections it was possible to see a connection with a vellus hair follicle by an epithelial pedicle. The histologic examination of one of the mother’s papules on the forehead showed a large round cystic structure with histologic features of EVHC. Close to the cyst wall, serial sections showed flattened sebaceous gland lobules. The histologic findings of the second biopsy taken from the chest showed the typical features of a steatocystoma. Conclusions: The relationship between milia, SM and EVHC is discussed; the three diseases should be considered as subtypes of multiple pilosebaceous cysts that may all present overlapping histologic features. The different level of the pilosebaceous duct where the cyst originates should explain the different clinical manifestations.

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Section: Discussionsupporting

confidence: 55%

Persistent Milia, Steatocystoma multiplex and Eruptive Vellus Hair Cysts: Variable Expression of Multiple Pilosebaceous Cysts within an Affected Family

et al. 1998

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“…Occasionally, however, the cavity of SM contains vellus hairs and follicular structures are also found adjacent to the cyst. Moreover, sebaceous glands have sometimes been observed around the cysts in EVHC (13), and one case was reported in which the wall of the cyst had sebaceous gland cells (4). As Sanchez-Yus and Requena emphasized (14), multiple biopsies are necessary to conclude that the lesions are EVHC or SM.…”

Section: The Coexistence Of Eruptive Vellus Hair Cysts and Steatocystmentioning

confidence: 98%

The Coexistence of Eruptive Vellus Hair Cysts and Steatocystoma Multiplex

Ogawa

Nogita

Kawashima

1992

The Journal of Dermatology

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“…There are laminated and amorphous keratin and vellus hairs within the cyst. The histological features are distinct and can be differentiated from epidermal cysts, steatocystoma multiplex, milia, dermoid cysts and pilar cysts [1, 2, 3]. The exact etiology is unclear; some lesions show dominant inheritance [4], while others have congenital characteristics [5]and are associated with congenital pachyonychia [6, 7]or ectodermal dysplasia [8, 9].…”

Section: Introductionmentioning

confidence: 99%

“…The exact etiology is unclear; some lesions show dominant inheritance [4], while others have congenital characteristics [5]and are associated with congenital pachyonychia [6, 7]or ectodermal dysplasia [8, 9]. Eruptive vellus hair cysts may be caused by a developmental abnormality of vellus hair follicles, predisposing them to occlusion at their infundibular level [1, 2, 3]. This appears to confirm a hamartomatous origin of eruptive vellus hair cysts.…”

Section: Introductionmentioning

confidence: 99%

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Eruptive Vellus Hair Cyst in Patients with Chronic Renal Failure

Mieno

Fujimoto²,

Tajima³

2004

Dermatology

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Two cases of eruptive vellus hair cysts associated with chronic renal failure are reported. Histologically the lesions of both cases showed cystic structures in the dermis lined by squamous epithelium which contained varying amounts of vellus hair shafts. Immunohistochemical studies using monoclonal anti-AGE (advanced glycation end product) antibody demonstrated that keratinous materials within the cystic structures were immunoreactive to the antibody, whereas those of cystic lesions (epidermal cyst, eruptive vellus hair cyst, steatocystoma multiplex, trichofolliculoma and trichilemmal cyst) seen in otherwise healthy individuals were negative. Because it has been reported that plasma and skin levels of AGE are elevated in renal failure patients, AGE-modified keratinous materials may be associated with the formation of cystic structures by stimulating the occlusion of the epithelium.

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Eruptive vellus hair cysts

Cited by 21 publications

References 0 publications

Persistent Milia, Steatocystoma multiplex and Eruptive Vellus Hair Cysts: Variable Expression of Multiple Pilosebaceous Cysts within an Affected Family

Persistent Milia, Steatocystoma multiplex and Eruptive Vellus Hair Cysts: Variable Expression of Multiple Pilosebaceous Cysts within an Affected Family

The Coexistence of Eruptive Vellus Hair Cysts and Steatocystoma Multiplex

Eruptive Vellus Hair Cyst in Patients with Chronic Renal Failure

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