Eruption Resembling Erythema gyratum repens in Linear IgA Dermatosis

Abstract

We report a case of linear IgA dermatosis associated with eruptions resembling erythema gyratum repens in a 62-year-old man. The patient revealed no clinical and laboratory evidence of an underlying malignancy. The presence of eruptions similar to erythema gyratum repens during the course of bullous dermatoses has been described in only eight reports.

Erythema gyratum repens-like eruption in a patient with epidermolysis bullosa acquisita associated with ulcerative colitis

“…Nevertheless, the figurate eruption resembling EGR represents a particular clinical feature of this patient that has not yet been reported in patients with EBA. EGR may be very rarely associated with pemphigoid diseases 5–9 . Although EGR usually represents an ominous sign heralding an associated neoplasm, our patient as well as several previously reported cases 6,7,9 clearly demonstrate that in patients with autoimmune blistering diseases such figurate erythema may occur in the absence of neoplasia.…”

“…Inflammatory bowel diseases (IBD) may be associated with autoimmunity to type VII collagen 3,4 . Erythema gyratum repens (EGR), an obligate paraneoplastic syndrome, may occur in patients with pemphigoid diseases 5–9 . To the best of our knowledge, EGR has not been previously described in EBA.…”

Erythema gyratum repens‐like eruption occuring in resolving psoriasis during methotrexate therapy

“…Other than psoriasis, EGR is known to occur during resolution of pityriasis rubra pilaris, as well as bullous dermatoses like bullous pemphigoid and linear IgA disease. [9][10][11][12] Such associations may exemplify an extremely unusual clinical presentation of the primary dermatoses in question (i.e., ''EGR-like'' eruption). Alternatively, they may represent a ''true'' EGR seen in course of other nonneoplastic conditions.…”

An eczema-like, pruritic, nonbullous form of bullous pemphigoid

“…This case indicates that a lack of blisters does not necessarily exclude a diagnosis of BP, and supports previous reports suggesting gyrate erythema can be an initial manifestation of bullous disease. 5 BP can also present as gyrate erythema with or without malignancy, and it should not be ignored by physicians, and further studies are needed to elucidate the immunopathologic mechanisms that determine various clinical manifestations of BP. BP should be kept in mind as differential diagnosis in atypical, longlasting nonbullous pruritic lesions.…”