Erratum: UVA radiation causes DNA strand breaks, chromosomal aberrations and tumorigenic transformation in HaCaT skin keratinocytes

Wischermann, K.; Popp, Susanne; Moshir, Sharareh; Scharffetter‐­Kochanek, Karin; Wlaschek, Meinhard; Gruijl, Frank de; Hartschuh, Wolfgang; Greinert, Rüdiger; Volkmer, Beate; Faust, Alexandra; Rapp, Alexander; Schmezer, Peter; Boukamp, Petra

doi:10.1038/onc.2008.375

Cited by 2 publications

(1 citation statement)

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“…It was reported that UVA induce double-strand breaks (DSBs) by several authors [35,36]. It is accepted that replication-dependent DSB formation exists [37,38] and replication-independent DSB formation was also shown by several studies [39,40]. ROS are intermediates of the DNA damaging process and thus for the DSB formation.…”

Section: Skin Exposure To Uvmentioning

confidence: 99%

Evaluation of Inflammation by Cytokine Production Following Combined Exposure to Ultraviolet and Radiofrequency Radiation of Mobile Phones on 3D Reconstructed Human Skin In Vitro

Szilágyi

Németh

Bakos

et al. 2020

IJERPH

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The absorption of exposure to radiofrequency (RF) emitted by wireless devices leads to a high specific absorption rate in the skin. Ultraviolet (UV) radiation can induce several damages to the skin. The aim of this study was to examine whether combined, consecutive exposure to solar UV radiation and 1950 MHz RF exposure of third generation (3G) mobile system have any effect on inflammation processes in the skin. Under in vitro experiments, the inflammation process was examined by cytokines (IL-1α, IL-6, and IL-8) and MMP-1 enzyme secretion on 3D full thickness human skin model. The RF exposure was applied before or after UV irradiation, in order to study either the possible cooperative or protective effects of exposure to RF and UV. We did not find changes in cytokines due to exposure to RF alone. The RF exposure did not enhance the effects of UV radiation. There was a statistically not-significant decrease in cytokines when the skin tissues were pre-exposed to RF before being exposed to 4 standard erythemal dose (SED) UV compared to UV exposure alone. We found that RF exposure reduced the previously UV-treated MMP-1 enzyme concentration. This study might support the evaluation of the effects on the skin exposed to microwave radiation of 5G mobile technology.

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