Erratum to: Temporal characterization of serum metabolite signatures in lung cancer patients undergoing treatment

Abstract

The original version of this article unfortunately contains a mistake. The presentation of Fig. 2e and its caption are incorrect. The corrected Fig. 2e and its caption are given below.

A review of metabolism-associated biomarkers in lung cancer diagnosis and treatment

“…Serum metabolites collected before, during and after chemotherapy are useful in predicting disease progression and overall survival in lung cancer patients (Hao et al, 2016b, Hao et al, 2016a). Elevated levels of metabolites such as hydroxylamine and octadecan-1-ol were observed in patients with advanced stage disease, who did not survive chemotherapy (Hao et al, 2016b, Hao et al, 2016a).…”

“…Serum metabolites collected before, during and after chemotherapy are useful in predicting disease progression and overall survival in lung cancer patients (Hao et al, 2016b, Hao et al, 2016a). Elevated levels of metabolites such as hydroxylamine and octadecan-1-ol were observed in patients with advanced stage disease, who did not survive chemotherapy (Hao et al, 2016b, Hao et al, 2016a). On the other hand, amino acids glutamine, proline, valine, threonine and tyramine were abundant in patients in early stages of the disease, who had higher survival rates (Hao et al, 2016b, Hao et al, 2016a).…”

“…Elevated levels of metabolites such as hydroxylamine and octadecan-1-ol were observed in patients with advanced stage disease, who did not survive chemotherapy (Hao et al, 2016b, Hao et al, 2016a). On the other hand, amino acids glutamine, proline, valine, threonine and tyramine were abundant in patients in early stages of the disease, who had higher survival rates (Hao et al, 2016b, Hao et al, 2016a). Interestingly, metabolites such as glycine, phosphoric acid, pyroglutamic acid and octadecenoic acid are associated with advanced disease as well as higher survival and knowledge of these metabolites may prove useful in determination of an effective line of treatment for stage III-IV lung tumor patients (Hao et al, 2016b, Hao et al, 2016a).…”

“…On the other hand, amino acids glutamine, proline, valine, threonine and tyramine were abundant in patients in early stages of the disease, who had higher survival rates (Hao et al, 2016b, Hao et al, 2016a). Interestingly, metabolites such as glycine, phosphoric acid, pyroglutamic acid and octadecenoic acid are associated with advanced disease as well as higher survival and knowledge of these metabolites may prove useful in determination of an effective line of treatment for stage III-IV lung tumor patients (Hao et al, 2016b, Hao et al, 2016a). In addition to serum metabolites, higher levels of urine metabolites such as NANA, cortisol sulfate, creatine riboside and 561+ have also been associated with worse survival rates (Mathe et al, 2014).…”