Erratum to “Restless legs syndrome induced by citalopram: a psychiatric emergency?” [General Hospital Psychiatry 29 (2007) 72–74]

Perroud, Nader; Lazignac, Coralie; Baleydier, Bertrand; Cicotti, Andrei; Maris, Stella; Damsa, Cristian

doi:10.1016/j.genhosppsych.2007.01.007

Cited by 15 publications

(4 citation statements)

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“…Similarly, Ibiloglu described an akathisia episode secondary to metoclopramide short use in a 56-year-old male with gastroesophageal reflux disease [ 8 ], while Qiu and Lim reported acute akathisia in a young woman who was given an IV bolus to treat her gastroenteritis [ 9 ]. Other cases of iatrogenic RLS secondary to selective serotonin reuptake inhibitors (e.g., citalopram) have been published [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

An Unusual Case of an Acute Episode of Restless Leg Syndrome Following Oral Metoclopramide Therapy

Aljunaid

2024

Cureus

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Restless leg syndrome (RLS) is a chronic disorder characterized by a compulsive urge to move the legs, accompanied by various subjective symptoms and a distinctive nyctimeral pattern. A negligent entity is drug-induced RLS, which may be challenging to recognize by practitioners due to its rarity. Among various drugs that can induce or exacerbate RLS, metoclopramide is notable; however, the literature primarily describes cases related to its intravenous forms. In this case presentation, a 33-year-old male experienced drug-related gastrointestinal (GI) symptoms after starting semaglutide for weight loss. Semaglutide was discontinued, and oral metoclopramide was administered to manage the GI symptoms. Subsequently, he developed RLS-like symptoms, which resolved within 48 hours of stopping metoclopramide. His family history included chronic RLS. Laboratory tests were normal. The case highlights a potential link between drug administration and transient RLS symptoms. This case suggests that RLS can be a rare, reversible side effect of oral metoclopramide. It emphasizes the need for careful monitoring of RLS symptoms in patients using this drug and highlights the variability of side effects depending on the method of drug administration. The case serves as a reminder of the unpredictable nature of drug reactions and the importance of vigilance in pharmacotherapy.

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Section: Discussionmentioning

confidence: 99%

An Unusual Case of an Acute Episode of Restless Leg Syndrome Following Oral Metoclopramide Therapy

Aljunaid

2024

Cureus

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“…It should be underlined that mirtazapine has the highest risk for RLS among second-generation antidepressants [3], typically within the first week, and provokes periodic limb movements even in healthy subjects [4]. However, a similar case report had been described with citalopram [5].…”

Section: Sirmentioning

confidence: 96%

Exacerbation of restless legs syndrome presenting as a psychiatric emergency

Maestri

Carnicelli

Coscio

et al. 2013

Euro J of Neurology

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“…But antipsychotics, antiepileptics, antihistamines, and antidepressants could induce or worsen the RLS (Patatanian and Claborn, 2018). Antidepressant-induced RLS has been described for selective serotonin reuptake inhibitors (SSRI), mirtazapine, and also serotonin and noradrenaline reuptake inhibitors (SNRI) (Simpson, 1996; Bakshi, 1996; Hargrave and Beckley, 1998; Bonin et al ., 2000; Ağargün et al ., 2002; Bahk et al , 2002; Pae et al , 2004; Prospero-Garcia et al , 2006; Oztürk et al ., 2006; Perroud et al , 2007; Page et al , 2008; Park et al , 2009; Chopra et al ., 2011; Makiguchi et al , 2015; Nikolaou et al , 2015).…”

Section: Introductionmentioning

confidence: 99%

Frequency, risk factors, and impacts on quality of life of the restless legs syndrome and side effects among antidepressant users in a tertiary hospital: an observational cross-sectional study

Erdem

Kara²,

Ozcelik³

et al. 2023

International Clinical Psychopharmacology

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Restless leg syndrome (RLS) is a common but underestimated sensorimotor disorder that significantly affects the quality of life (QoL) which can be induced by antidepressants. This study aims to investigate the frequency and potential risk factors of RLS and side effects in selective serotonin reuptake inhibitors/ serotonin and noradrenaline reuptake inhibitors (SSRI/SNRI) users. This cross-sectional study included 198 outpatients who received SSRI/SNRI for 4-8 weeks. Clinical evaluation was performed using the International Restless Leg Syndrome Study Group rating scale for RLS, Udvalg for Kliniske Undersøgelser side effects rating scale, and a short form 36 (SF-36) questionnaire for QoL. The frequency of RLS was 25%. RLS significantly increased with smoking and habituality. Also, habituality increased neurologic side effects reporting. The use of antipsychotics and calcium channel blockers decreased reporting of autonomic side effects. QoL decreased with RLS, psychiatric, neurologic, autonomic, and other side effects in different domains of SF-36. These findings suggested that SSRI/SNRI use could be associated with a higher risk of RLS, especially in smokers. QoL could be influenced negatively by RLS and all side effects. However, further prospective studies are needed to confirm these associations in large samples.

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Erratum to “Restless legs syndrome induced by citalopram: a psychiatric emergency?” [General Hospital Psychiatry 29 (2007) 72–74]

Cited by 15 publications

References 0 publications

An Unusual Case of an Acute Episode of Restless Leg Syndrome Following Oral Metoclopramide Therapy

An Unusual Case of an Acute Episode of Restless Leg Syndrome Following Oral Metoclopramide Therapy

Exacerbation of restless legs syndrome presenting as a psychiatric emergency

Frequency, risk factors, and impacts on quality of life of the restless legs syndrome and side effects among antidepressant users in a tertiary hospital: an observational cross-sectional study

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