Erratum to: Preventive strategies aimed at reducing the health risks of aflatoxin B1

Valencia-Quintana, Rafael; Sánchez-Alarcón, Juana; Tenorio, María Guadalupe; Deng, Youjun; Waliszewski, Stefan M.; Valera, Miguel Ángel

doi:10.1007/s13530-012-0138-1

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“…Among mycotoxicosis described in humans, aflatoxicosis is of the greatest concern; repetitive aflatoxin outbreaks were reported in recent years in Kenya, India, and Malaysia, often accompanied by fumonisins (Shephard, 2004; Lewis et al, 2005). In acute mycotoxication, it can cause impaired growth in children, vomiting, abdominal pain, pulmonary edema and liver necrosis (Valencia-Quintana et al, 2012).…”

Section: Aflatoxinsmentioning

confidence: 99%

Involvement of Ahr Pathway in Toxicity of Aflatoxins and Other Mycotoxins

et al. 2019

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The purpose of this review is to present information about the role of activation of aflatoxins and other mycotoxins, of the aryl hydrocarbon receptor (AhR) pathway. Aflatoxins and other mycotoxins are a diverse group of secondary metabolites that can be contaminants in a broad range of agricultural products and feeds. Some species of Aspergillus, Alternaria, Penicilium, and Fusarium are major producers of mycotoxins, some of which are toxic and carcinogenic. Several aflatoxins are planar molecules that can activate the AhR. AhR participates in the detoxification of several xenobiotic substances and activates phase I and phase II detoxification pathways. But it is important to recognize that AhR activation also affects differentiation, cell adhesion, proliferation, and immune response among others. Any examination of the effects of aflatoxins and other toxins that act as activators to AhR must consider the potential of the disruption of several cellular functions in order to extend the perception thus far about the toxic and carcinogenic effects of these toxins. There have been no Reviews of existing data between the relation of AhR and aflatoxins and this one attempts to give information precisely about this dichotomy.

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Section: Aflatoxinsmentioning

confidence: 99%