Erratum to: Osteoid osteoma and osteoblastoma of the spine: a review of the literature

Saccomanni, Bernardino

doi:10.1007/s12178-012-9113-3

Cited by 14 publications

(18 citation statements)

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“…Osteoblastomas are relatively rare benign bone tumors, accounting for about 1% of all primary bone tumors and 3% of benign bone tumors (1). About half of osteoblastomas have a spinal location; 20% are located in the cervical spine within the spinous and transverse processes, and another 17% of spinal osteoblastomas are found in the sacrum.…”

Section: Discussionmentioning

confidence: 99%

“…The long tubular bones are also common sites of involvement, with a lower-extremity preponderance. In any case, spinal osteoblastomas mostly involve the posterior spinal elements, including pedicles, spinous, and transverse processes and lamina, with the thoracolumbar spine being most frequently affected (1,4). The pathogenesis of osteoblastoma remains largely unknown.…”

Section: Discussionmentioning

confidence: 99%

“…Most patients are young men, usually complaining of a dull, localized pain for more than a year before the diagnosis is confirmed (1,2). We report the case of a destructive cervical osteoblastoma at C5 in a young man, initially presenting with spastic quadriparesis.…”

Section: Introductionmentioning

confidence: 95%

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Destructive Cervical Spine Osteoblastoma at C5 in a Young Patient Initially Presenting with Quadriparesis: Case Report and Review of the Literature

Panagiotopoulos

Masmanidis

Tzortzidis

et al. 2013

The Journal of Emergency Medicine

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Destructive Cervical Spine Osteoblastoma at C5 in a Young Patient Initially Presenting with Quadriparesis: Case Report and Review of the Literature

Panagiotopoulos

Masmanidis

Tzortzidis

et al. 2013

The Journal of Emergency Medicine

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“…The most common area of involvement is the cervical spine, followed by the lumbar spine and sacrum. In the spine, osteoblastoma is usually confined to the posterior elements (8,9).…”

Section: Discussionmentioning

confidence: 99%

Osteoblastoma Is a Metabolically Active Benign Bone Tumor on 18F-FDG PET Imaging

Al-Muqbel

Al-Omari

Audat

et al. 2013

Journal of Nuclear Medicine Technology

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We describe a case of a 9-y-old girl who on 18 F-FDG PET imaging was found to have a highly metabolically active sacral tumor with an average standarized uptake value of 6.2. The tumor was proven to be osteoblastoma by pathologic examination. Osteoblastoma is a relatively rare benign primary bone tumor and occurs predominantly in patients younger than 20 y. The most common area of involvement is the spine. Osteoblastoma has been reported to be metabolically active on 18 F-FDG PET imaging, with an average standarized uptake value of 3.2, which renders 18 F-FDG PET imaging unable to differentiate benign from malignant primary bone tumors. To our knowledge, only 5 cases of osteoblastoma evaluated by 18 F-FDG PET imaging have been reported in the literature; all were metabolically active on 18 F-FDG PET imaging. The objective of this case report is to show that a metabolically active primary bone tumor on 18 F-FDG PET imaging might be benign and not necessarily malignant. PETi s an important imaging modality for a patient with malignancy. 18 F-FDG PET imaging is commonly used for staging and restaging cancer. 18 F-FDG accumulates in cancer cells because of their increased glucose metabolism. However, increased glucose metabolism is not specific to malignancy. Some benign bone lesions may accumulate 18 F-FDG in amounts similar to those seen for malignant bone tumors (1). Osteoblastoma is an uncommon benign and vascular osteoid-forming bone tumor (2). In the literature, we could find only 5 osteoblastoma cases involving 18 F-FDG PET evaluation, all of which revealed increased 18 F-FDG uptake (1-4). Here, we present another case of sacral osteoblastoma that revealed increased metabolic activity on 18 F-FDG PET imaging. The objective of this case report is to show that a metabolically active primary bone tumor on 18 F-FDG PET imaging may be a benign tumor such as osteoblastoma and not necessarily malignant. CASE REPORTThe orthopedic clinic referred a 9-y-old girl to the nuclear medicine department for whole-body bone scanning. She had a 1-mo history of left hip pain radiating to the left thigh. Two weeks before surgery, she started to complain of intermittent abdominal pain, constipation, and occasional difficulty with urination. Initially, she was evaluated by simple radiography of the hip, with normal results. Wholebody bone scanning was performed and found an isolated focal osteoblastic lesion involving the L5 and S1 vertebrae (Fig. 1). Three days later, the patient underwent lumbar spine MR imaging, which demonstrated a large mass (measuring 4 · 2.5 cm) originating from the left sacral ala at the S1 and S2 levels. The mass was invading the spinal canal and the left S1 and S2 foramina and extended upward to the left L5-S1 neural exit canal, causing L5-S1 neural foramina expansion (Fig. 2). Five days later, the patient underwent lumbar spine CT, which demonstrated an enhancing soft-tissue mass causing expansion of the left S1 intervertebral foramen and showing dumb-bell growth inside the spinal canal and outside the l...

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“…While osteoid osteomas are typically treated with pain control, osteoblastomas are reportedly capable of malignant transformation. 5,6 Osteoblastomas, along with other primary bones tumors, are thought to elicit a localized inflammatory response within the bone that can lead to an aggressive MRI appearance. [7][8][9] However, this area of marrow edema and inflammation is free of tumor cells.…”

Section: Introductionmentioning

confidence: 99%

A clinicopathologic correlation in osteoblastoma of the spine in a child

Patel

Fox

Fahim

et al. 2011

Journal of Clinical Neuroscience

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Erratum to: Osteoid osteoma and osteoblastoma of the spine: a review of the literature

Cited by 14 publications

References 0 publications

Destructive Cervical Spine Osteoblastoma at C5 in a Young Patient Initially Presenting with Quadriparesis: Case Report and Review of the Literature

Destructive Cervical Spine Osteoblastoma at C5 in a Young Patient Initially Presenting with Quadriparesis: Case Report and Review of the Literature

Osteoblastoma Is a Metabolically Active Benign Bone Tumor on 18F-FDG PET Imaging

A clinicopathologic correlation in osteoblastoma of the spine in a child

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