2019
DOI: 10.1140/epjc/s10052-018-6520-7
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Erratum to: Measurement of the W boson polarisation in $$t\bar{t}$$ t t ¯ events from pp col

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Cited by 9 publications
(8 citation statements)
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“…However, to date, overall nuclear morphology has yet to be thoroughly examined in disease relevant cell types. Despite prior work examining the nuclear lamina in G 4 C 2 and DPR overexpression based model systems [ 18 , 37 ], which concluded that there were nuclear membrane alterations in those models, our current analyses using a large number of iPSC lines and postmortem patient tissues suggest that there are in fact no overt alterations to overall nuclear morphology or the frequency of Lamin B1 invaginations in C9orf72 ALS/FTD. While a previous study in postmortem tissue characterized nuclear morphology on the basis of “abnormal” vs “normal” [ 29 ], here we comprehensively evaluated nuclear shape in 2D and 3D using measures of circularity and sphericity in iPSNs differentiated from young and aged iPSCs as well as postmortem motor cortex.…”
Section: Discussioncontrasting
confidence: 74%
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“…However, to date, overall nuclear morphology has yet to be thoroughly examined in disease relevant cell types. Despite prior work examining the nuclear lamina in G 4 C 2 and DPR overexpression based model systems [ 18 , 37 ], which concluded that there were nuclear membrane alterations in those models, our current analyses using a large number of iPSC lines and postmortem patient tissues suggest that there are in fact no overt alterations to overall nuclear morphology or the frequency of Lamin B1 invaginations in C9orf72 ALS/FTD. While a previous study in postmortem tissue characterized nuclear morphology on the basis of “abnormal” vs “normal” [ 29 ], here we comprehensively evaluated nuclear shape in 2D and 3D using measures of circularity and sphericity in iPSNs differentiated from young and aged iPSCs as well as postmortem motor cortex.…”
Section: Discussioncontrasting
confidence: 74%
“…Given the role of the nuclear lamina in the compartmentalization of the nucleus and cytoplasm as well as the organization and coordination of nuclear functions [ 9 ], it has been hypothesized that the C9orf72 HRE can also impact global nuclear morphology. Multiple reports have suggested that nuclear lamina disruptions are a prevalent pathological feature of C9orf72 ALS/FTD [ 7 , 18 , 24 , 37 ]. However, many of these studies were conducted in non-neuronal cells [ 7 , 18 ] or in the context of highly artificial overexpression of G 4 C 2 repeats or individual DPRs [ 7 , 18 , 37 ].…”
Section: Introductionmentioning
confidence: 99%
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“…Events are selected (preselection) if they pass several quality cuts and requirements to select final states with one reconstructed electron or muon and five or more jets [80,81]. A reconstructed primary vertex with at least five associated tracks is required.…”
Section: Event Selection and Reconstructionmentioning
confidence: 99%
“…Besides resonance searches in the tt mass spectrum and modifications of QCD interactions, the most interesting corner to look for New Physics is the electroweak top quark interactions. Prominent examples are the analyses of tt + Z/W/H [42][43][44][45] final states or the W -helicity fractions in top quark decays [46,47], which yield direct on-shell sensitivity to the couplings between top quarks and the electroweak bosons. Global fits of New Physics contributions in terms of dimension-six operators relevant for the top quark sector have been carried out in refs.…”
Section: Introductionmentioning
confidence: 99%