Erratum to Itraconazole: a review of its pharmacological properties and therapeutic use in the management of superficial fungal infections

Inhibition of Fas/FasL mRNA expression and TNF-α release in concanavalin A-induced liver injury in mice by bicyclol

“…Although a number of drugs such as interferon-2α and lamivudine have been used in the treatment of viral hepatitis, the efficacy of these drugs is still limited and some side effect are severe [2,3] . Therefore, it is necessary to develop new anti-hepatitis drugs.…”

Effect of econazole on Ca2+ signaling in human colorectal adenocarcinoma cells

“…As Ca 2+ entry into the cytoplasm influences the expression and activity of intracellular kinases and gene expression [23][24][25][26], we conclude that econazole may modify the physiology of human adenocarcinoma HT29 cells. IP 3 and diaylglycerol, which activates PKC. However, econazole-induced Ca 2+ increase was not inhibited by treating the cells with staurosporine, a PKC inhibitor, thus suggesting that the [Ca 2+ ] i rise observed after treating the cells with econazole was apparently not dependent on PKC activation.…”

“…The discovery of the antifungal activity of azole compounds represented an important therapeutic advance [1][2][3][4][5]. Within them, Econazole, widely used as an antifungal drug [6], is currently further investigated for additional therapeutic effects.…”

Steroid resistant nephrotic syndrome in a child with chronic hepatitis B infection

“…5 IFN alfa has been shown to induce the proliferation of natural killer cells, which are helpful in clearing the virally infected cells. 6 IFN therapy has a beneficial effect in 30e40% of patients with chronic hepatitis B who respond by clearing HBeAg from serum.…”