Erratum to “Antimicrobial activity and phytochemical analyses of Polygonum aviculare L. (Polygonaceae), naturally growing in Egypt” [Saudi J. Biol. Sci. 17(1) (2010) 57–63]

Chemistry and biological activities of hetisine-type diterpenoid alkaloids

“…The common oxygenated substituents found in hetisine-type DAs are hydroxyl (OH), ketone carbonyl (]O), and ester groups such as acetyl (Ac), isobutyl (iBu), 2-methylbutyryl (MeBu), and benzoyl (Bz) groups. Rarely, palmasine (20) and palmadine (21) from A. palmatum feature an uncommon cinnamoyl (Cn) group at C-13, 31 and acoridine (48), Guan-fu bases R (39) and O (50) from A. coreanum possess a propionyl (Pr) group at C-2. [32][33][34] Most hetisine-type DAs have an exocyclic terminal olenic bond at C-16 and C-17.…”

“…3 In addition, hetisine-type DAs have been found in plants of the genera Rumex and Polygonum in the family Polygonaceae, including orientinine (79), panicudine (106), and acorientine (115) from Rumex pictus 74 and panicudine (106) from Polygonum aviculare. 20 Hetisine-type DA is the only type of DA that has been found in the polygonaceae family, which widens the distribution of DAs.…”

“…98 The bioactivity-guided separation of the chloroform fraction with antimicrobial activities from P. aviculare led to the isolation of the hetisine-type DA panicudine (106), which was evaluated for its antimicrobial activity against both Gram-negative bacteria (Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Salmonella typhi, Salmonella paratyphi and Shigella exneri), Gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis, and Streptococcus pyogenes) and fungi by determining the diameter of the inhibition zone using the paper disk diffusion method. 20 Consequently, panicudine (106) displayed considerable activity against all tested Gram-negative and Gram-positive organisms (diameter of zone of inhibition ranging from 5-23 mm at 0.4-400 mg mL À1 ), with the exception of Candida albicans. Hetisine-type DAs have also shown certain antiviral activity.…”

“…Since the time when hetisine-type was dened in 1960s, 15 numerous compounds have been isolated and identi-ed, making this type the most abundant subtype of C 20 -DAs in terms of quantity. In addition, preliminary studies have revealed that hetisine-type DAs have a wide range of pharmacological actions, including antiarrhythmic, 16,17 antitumor, 18,19 antimicrobial and insecticidal activities, 20,21 as well as effects on peripheral vasculature. 22 In particular, hetisine-type DAs possess more prominent antiarrhythmic effects than the other DAs along with low toxicity, which highlights their potential in antiarrhythmic drug discovery.…”

Phytochemical screening and antibacterial properties of Sungkai (Peronema canescens Jack.) leaf extract and fraction

“…The recent development of bacterial resistance to commonly used antibiotics has required the exploration of novel antibacterial compounds. Many kinds of investigations have been done utilizing plant extracts to assess antimicrobial activity and identify novel antimicrobial compounds [1]. Numerous plants with significant antimicrobial properties have been identified [2]; thus, the endeavours of scientists to identify plants with prospective antimicrobial properties have been fruitful.…”