Erratum to: A review of α-amylase inhibitors on weight loss and glycemic control in pathological state such as obesity and diabetes

Abstract

The original version of this article contained a mistake on the name of the author. Instead of Najafian Mahmood it should be Mahmood Najafian.

The Effect of Aspalathin on Levels of Sugar and Lipids in Streptozotocin-Induced Diabetic and Normal Rats

“…2016; 18(11):e4963. 5 to be among top causes of death in the recent years [1,2]. Furthermore, as a chronic disease, diabetes is accompanied with serious kinds of complications such as vasculopathy, nephropathy, neuropathy and retinopathy [20][21][22].…”

“…Inhibition of carbohydrate digestion or absorption can decrease calorie intake to promote weight loss and combat obesity. It is also a mechanism for reducing hyperglycemia in diabetic subjects [1]. Being obese increases the risk of arthritis, dyslipidemia, hypertension, diabetes, and coronary artery disease [2].…”

“…These compounds have been shown to possess beneficial effects in diabetes, cardiovascular diseases, atherosclerosis, allergy, inflammation, cancer, asthma and osteoporosis [7][8][9][10]. Flavonoids based on differences in molecular backbone structure may be divided into eight different classes (flavonols, flavones, flavanones, catechins, anthocyanidins, isoflavones, dihydroflavonols, and chalcones) [1]. Flavonoid-rich fractions of plants have also been reported to be effective as antihyperglycemic and antihyperlipidemic agents in animal models of diabetes [11].…”

“…Flavonoid-rich fractions of plants have also been reported to be effective as antihyperglycemic and antihyperlipidemic agents in animal models of diabetes [11]. Plants derived polyphenols such as quercetagetin, fisetin, and quercetin, which belong to the flavonoid family, have been shown to be effective inhibitors of mammalian alpha-amylase with IC50s in the order of µM [1]. Aspalathin (Asp) is the major active dihydrochalcones found in green rooibos, which have been reported many interesting biological properties [12].…”

Conversion of Curcumin into Heterocyclic Compounds as Potent Anti-diabetic and Anti-histamine Agents

“…8) Flavonoid-rich fractions of plants have been reported to be effective as antihyperglycemic and antihyperlipidemic agents in animal models of diabetes. 9) Plants derived polyphenols such as quercetagetin, fisetin and quercetin, which belong to the flavonoid family have been shown to be effective inhibitors of mammalian alpha-amylase with IC 50 s in the order of micromolar. 10) Since curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) could be viewed as a flavonoid of polyphenolic compounds, in this investigation we researched the inhibitory effect of curcumin on α-amylase and the effect of curcumin orally on blood glucose levels in streptozotocin (STZ) induced diabetic and normal rats.…”