The Kuramoto–Velarde equation describes slow space-time variations of disturbances at interfaces, diffusion–reaction fronts and plasma instability fronts. It also describes Benard–Marangoni cells that occur when there is large surface tension on the interface in a microgravity environment. Under appropriate assumption on the initial data, of the time T, and the coefficients of such equation, we prove the well-posedness of the classical solutions for the Cauchy problem, associated with this equation.