Erosive candidiasis of the scalp, followed by the reappearance of black hair after 40 years

Verbov, Julian

doi:10.1111/j.1365-2133.1981.tb00806.x

Cited by 21 publications

(10 citation statements)

References 6 publications

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“…12 The return to original hair color in these individuals may reflect repopulation of the hair bulb melanogenic zone in response to these stimuli. 12 The return to original hair color in these individuals may reflect repopulation of the hair bulb melanogenic zone in response to these stimuli.…”

Section: Discussionmentioning

confidence: 99%

Repigmentation of Poliosis After Epithelial Grafting for Vitiligo

Awad¹

2013

Dermatologic Surgery

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Re-coloring of poliosis with vitiligo is possible but was unexpected because of the difference in mechanism and signaling required between hair bulb melanization and the surface skin. One likely mechanism to explain this change is that melanocyte stem cells are stimulated and migrate to supply hair bulbs with new mature melanocytes. Epithelial grafting of vitiligo with poliosis in hairy areas should be a treatment of choice when white hair tufts cause cosmetic disfigurement.

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Section: Discussionmentioning

confidence: 99%

Repigmentation of Poliosis After Epithelial Grafting for Vitiligo

Awad¹

2013

Dermatologic Surgery

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“…[6] Usually, the process is progressive and permanent though there are occasional reports of re-pigmentation of previously nonpigmented hair. [789]…”

Section: Discussionmentioning

confidence: 99%

Prospective analytical controlled study evaluating serum biotin, vitamin B₁₂, and folic acid in patients with premature canities

et al. 2017

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Background:Premature canities is a common yet unfathomed disorder. The evidence for the role of micronutrient deficiency in premature canities is not well established.Aim:The present study was undertaken to evaluate the micronutrient levels in Indian patients with premature canities as compared to controls.Materials and Methods:We conducted a case–control study in 52 self-reporting patients with premature canities (<20 years age). Micronutrient levels including serum Vitamin B12, biotin, and folic acid were assessed and compared among the patients and controls.Results:We observed that mean serum Vitamin B12 (198.07 ± 88.98 pg/ml in cases vs. 343.07 ± 143.06 pg/ml in controls, P = 0.000), folic acid (6.22 ± 2.46 ng/ml in cases vs. 8.49 ± 4.18 ng/ml in controls, P = 0.01), and biotin (252.71 ± 18.79 pg/ml in cases vs. 266.47 ± 30.44 pg/ml in controls, P = 0.013) levels were significantly lower in cases as compared to the controls.Conclusion:In view of the dark hair and many prevailing myths, premature canities is a significant problem in Asians with profound psychosocial impact. This study unveils the association with Vitamin B12, folic acid, and biotin deficiencies. Larger studies are recommended to arrive on a logical conclusion.

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“…[78][79][80] Hair darkening has also been described after X-ray irradiation and following electron beam therapy. [51] Shaffrali et al reported darkening of gray hair in two patients with porphyria cutanea tarda.…”

Section: Management Managementmentioning

confidence: 99%

Premature graying of hair

Pandhi¹,

Khanna²

2013

Indian J Dermatol Venereol Leprol

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Premature graying is an important cause of low self-esteem, often interfering with socio-cultural adjustment. The onset and progression of graying or canities correlate very closely with chronological aging, and occur in varying degrees in all individuals eventually, regardless of gender or race. Premature canities may occur alone as an autosomal dominant condition or in association with various autoimmune or premature aging syndromes. It needs to be differentiated from various genetic hypomelanotic hair disorders. Reduction in melanogenically active melanocytes in the hair bulb of gray anagen hair follicles with resultant pigment loss is central to the pathogenesis of graying. Defective melanosomal transfers to cortical keratinocytes and melanin incontinence due to melanocyte degeneration are also believed to contribute to this. The white color of canities is an optical effect; the reflection of incident light masks the intrinsic pale yellow color of hair keratin. Full range of color from normal to white can be seen both along individual hair and from hair to hair, and admixture of pigmented and white hair is believed to give the appearance of gray. Graying of hair is usually progressive and permanent, but there are occasional reports of spontaneous repigmentation of gray hair. Studies evaluating the association of canities with osteopenia and cardiovascular disease have revealed mixed results. Despite the extensive molecular research being carried out to understand the pathogenesis of canities, there is paucity of effective evidence-based treatment options. Reports of repigmentation of previously white hair following certain inflammatory processes and use of drugs have suggested the possibility of cytokine-induced recruitment of outer sheath melanocytes to the hair bulb and rekindled the hope for finding an effective drug for treatment of premature canities. In the end, camouflage techniques using hair colorants are outlined.

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Erosive candidiasis of the scalp, followed by the reappearance of black hair after 40 years

Abstract: SUMMARY A female aged 72 years developed an erosive pustular dermatosis of the anterior scalp from which Candida albicans was repeatedly cultured. The infected area was bald, but on recovery hair regrew and much of this was black although it had been white for the previous 40 years.

Cited by 21 publications

References 6 publications

Repigmentation of Poliosis After Epithelial Grafting for Vitiligo

Repigmentation of Poliosis After Epithelial Grafting for Vitiligo

Prospective analytical controlled study evaluating serum biotin, vitamin B₁₂, and folic acid in patients with premature canities

Premature graying of hair

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Erosive candidiasis of the scalp, followed by the reappearance of black hair after 40 years

Abstract: SUMMARY A female aged 72 years developed an erosive pustular dermatosis of the anterior scalp from which Candida albicans was repeatedly cultured. The infected area was bald, but on recovery hair regrew and much of this was black although it had been white for the previous 40 years.

Cited by 21 publications

References 6 publications

Repigmentation of Poliosis After Epithelial Grafting for Vitiligo

Repigmentation of Poliosis After Epithelial Grafting for Vitiligo

Prospective analytical controlled study evaluating serum biotin, vitamin B12, and folic acid in patients with premature canities

Premature graying of hair

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Prospective analytical controlled study evaluating serum biotin, vitamin B₁₂, and folic acid in patients with premature canities