Erkek Meme Kanserinde Prevalans ve Klinik Deneyimlerimiz

Abstract

ÖzetAmaç: Erkeklerde meme kanseri nadir rastlanan tümörlerdendir. Bu çalışmada meme polikliniğimize başvuran hastalardan meme kanseri tespit edilen erkek hastalar incelenmiştir. Yöntem: Haseki Eğitim ve Araştırma Hastanesi Genel Cerrahi Kliniği'nde meme kanseri tanısı ile opere edilen altı erkek hasta geriye dönük olarak incelenmiştir. Hastalar, Ocak 2009-Aralık 2012 tarihleri arasında meme polikliniğine başvurup meme kanseri tanısı alan 268 hasta arasından seçilmiştir. Bulgular: Hastaların yaş ortalaması 61 yıl (50-73) idi. En sık başvuru nedeni memede ele gelen kitleydi. Tümör çapı ortalaması 2.58 cm (2-3.5) idi. Olguların tümüne modifiye radikal mastektomi uygulandı. Tüm hastalarda preoperatif kor biyopside olduğu gibi postoperatif histopatolojik olarak invazif duktal karsinom tanısı doğrulandı. Preoperatif yapılan görüntülemelerde ve postoperatif patolojik incelemelerde tüm hastalarda aksiller lenf nodu tutulumu saptandı. Hastalara uygun adjuvan tedaviler uygulandı. Sonuç:Erkek meme kanseri ile kadın meme kanseri aynı evrede ise benzer prognoza sahiptir. Meme kanseri erkeklerde çok nadir rastlanır ancak tanıda gecikme olduğundan çoğu vakada ileri evrede saptanır. (Ha se ki T›p Bül te ni 2013; 51: 99-101) AnahtarKelimeler:Erkek, meme, kanser Abs tract Aim:Male breast carcinomas are very rare tumors. In this study, we aimed to evaluate the male patients who were diagnosed with breast carcinoma and admitted to our outpatient clinic. Methods: Among 268 patients diagnosed with breast carcinoma in the General Surgery Department at Haseki Training and Research Hospital between January 2009 and December 2012, a total of six male patients, who were operated on for breast cancer, were retrospectively reviewed. Results:The mean age of the subjects was 61 years (range: 50-73). The most clinical presentation was a palpable breast mass. The mean diameter of the lesions was 2.58 cm (range: 2.0-3.5 cm). All patients underwent modified radical mastectomy. The postoperative histopathology confirmed the diagnosis of invasive ductal carcinoma consistent with the results of preoperative core biopsies. Preoperative imaging studies and postoperative pathological analyses indicated axillary lymph node positivity. Postoperative adjuvant therapies were performed. Conclusion: The prognosis of breast cancer is similar in male and female patients when detected in similar stages. Although breast cancer is very rare in men, it is detected in advanced stage because of late diagnosis. (The Me di cal Bul le tin of Ha se ki 2013; 51: 99-101) Ya z›fl maAd re si/Ad dressforCor res pon den ce:Cihad Tatar

Male breast cancer: clinicopathological, immunohistochemical and radiological study

“…Although the mean tumor size reported in the literature is 2 to 3.5 cm, it can vary between 0.5 and 12.5 cm (2,3,13).…”

“…The most common complaint is generally a palpable mass in the breast. Although signs such as nipple discharge, mass, contraction, scarring, and redness in the breast are seen in many cases, they are generally ignored and delays in diagnosis are therefore experienced as the hospital admissions are late ( 13 ). In our series, the most common complaint was swelling of the breast, followed by a non-healing wound on the nipple, bloody discharge, and redness.…”

“…Although the mean tumor size reported in the literature is 2 to 3.5 cm, it can vary between 0.5 and 12.5 cm ( 2 , 3 , 13 ). In our series, tumor size ranged from 0.6 to 4.5 cm, with an average of 2.35 cm, in accordance with the literature.…”

“…However, its incidence has recently been increasing with approximately 2000 to 2500 new cases reported annually in the United States (1,3,(8)(9)(10)(11)(12). Although male breast cancer occurs in all age groups, it is frequently observed between 60 and 70 years of age on average (2,3,10,(12)(13)(14). Genetic factors, BRCA2 mutations, family history, obesity, Klinefelter's syndrome, gynecomastia, liver disease, orchitis, undescended testicle, alcohol use, exogenous estrogen and testosterone use, and radiation are accused in the etiology (1,8,9,(15)(16)(17).…”

Synchronous male breast and colon cancer presenting with ileus: A case report

“…The incidence of breast cancer in men is 1 in 100,000; mostly presenting as ER and PR positive invasive ductal carcinomas [5] , [6] . Our patient too had ER +, PR + invasive ductal carcinoma.…”